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A Statistical Approach to the Pharmacokinetic Model
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 Title & Authors
A Statistical Approach to the Pharmacokinetic Model
Lee, Eun-Kyung;
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The Pharmacokinetic model is a complex nonlinear model with pharmacokinetic parameters that is some-times represented by a complex form of differential equations. A population pharmacokinetic model adds individual variability using the random effects to the pharmacokinetic model. It amounts to the nonlinear mixed effect model. This paper, reviews the population pharmacokinetic model from a statistical viewpoint; in addition, a population pharmacokinetic model is also applied to the real clinical data along with a review of the statistical meaning of this model.
Population pharmacokinetics;mixed effect model;nonlinear function;
 Cited by
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