JOURNAL BROWSE
Search
Advanced SearchSearch Tips
Perceptions of Anticoagulation Therapy and Medication Adherence among Patients taking Warfarin
facebook(new window)  Pirnt(new window) E-mail(new window) Excel Download
 Title & Authors
Perceptions of Anticoagulation Therapy and Medication Adherence among Patients taking Warfarin
Chu, Sang-Hui; Kang, Seok-Min; Kim, Do-Ree; Lee, Yoon-Ju;
  PDF(new window)
 Abstract
Purpose: This study was conducted to measure medication adherence and perceptions of anticoagulation therapy and its relationship to patients taking warfarin. Methods: in a cross-sectional survey, 150 patients taking warfarin who had visited an outpatient clinic of a cardiovascular center in Seoul were included as research subjects. Medication adherence was measured using a visual analogue rating scale (VAS). Barriers and attitudes toward adherence, and oral anticoagulation knowledge, were measured using a structured questionnaire. Participants` medical records also were reviewed to identify clinical characteristics. Results: About one third of the participants (30.7%) reported medication adherence as 100%. The major barriers to adherence were identified as "Forgetting the time of medication" and "Not carrying their medication". Overall attitudes toward medication adherence were high, but oral anticoagulation therapy knowledge was low. To determine the relationship of medication adherence and perceptions of anticoagulation therapy, participants were stratified into three groups, based on their medication adherence levels (high adherence, moderate adherence, low adherence). Participants in the high adherent group more likely to be older (OR: 1.04, 95% CI: 1.005-1.071) and to have positive attitudes toward medication adherence (OR: 1.12, 95% CI:1.013-1.229) compared to the other two groups. Conclusion: The results show that age and attitude exerts significant influence on medication adherence in patients taking warfarin.
 Keywords
Warfarin;Anticoagulation therapy;Perception;Medication adherence;
 Language
Korean
 Cited by
1.
만성 심부전 환자의 약물복용 이행 영향요인,추상희;고일선;이원희;유지수;강석민;정하윤;김두리;안지현;이윤주;

Journal of Korean Biological Nursing Science, 2012. vol.14. 3, pp.193-202 crossref(new window)
 References
1.
Baker, J. W., Pierce, K. L., & Ryals, C. A. (2011). INR goal attainment and oral anticoagulation knowledge of patients enrolled in an anticoagulation clinic in a Veterans Affairs medical center. Journal of Managed Care Pharmacy, 17 (2), 133-142.

2.
Briggs, A. L., Jackson, T. R., Bruce, S., & Shapiro, N. L. (2005). The development and performance validation of a tool to assess patient anticoagulation knowledge. Research in Social & Administrative Pharmacy, 1 (1), 40-59. crossref(new window)

3.
Davis, N. J., Billett, H. H., Cohen, H. W., & Arnsten, J. H. (2005). Impact of adherence, knowledge, and quality of life on anticoagulation control. The Annals of Pharmacotherapy, 39, 632-636. crossref(new window)

4.
Esmerio, F. G., Souza, E. N., Leiria, T. L., Lunelli, R., & Moraes, M. A. (2009). Constant use of oral anticoagulants: implications in the control of their adequate levels. Arquivos Brasileiros de Cardiologia, 93, 549-554.

5.
Hasan, S. S., Shamala, R., Syed, I. A., Basariah, N., Chong, D. W., Mei, T. K., et al. (2011). Factors affecting warfarin-related knowledge and INR control of patients attending physician- and pharmacist-managed anticoagulation clinics. Journal of Pharmacy Practice, 24, 485-493. crossref(new window)

6.
Hu, A., Chow, C. M., Dao, D., Errett, L., & Keith, M. (2006). Factors influencing patient knowledge of warfarin therapy after mechanical heart valve replacement. The Journal of Cardiovascular Nursing, 21, 169-175. crossref(new window)

7.
Hua, T. D., Vormfelde, S. V., Abu Abed, M., Schneider-Rudt, H., Sobotta, P., Friede, T., et al. (2011). Practice nursed-based, individual and video-assisted patient education in oral anticoagulation - Protocol of a cluster-randomized controlled trial. BMC Family Practice. 10, 12-17.

8.
Im, Y. (1998). The evaluation of therapeutic control with warfarin in patients with mechanical heart valve prostheses & it's relationship with patient's awareness. Unpublished master's thesis. Sook Myoung Women's University, Seoul.

9.
Kagansky, N., Knobler, H., Rimon, E., Ozer, Z., & Levy, S. (2004). Safety of anticoagulation therapy in well-informed older patients. Archives of Internal Medicine, 164, 2044-2050. crossref(new window)

10.
Kalichman, S. C., Amaral, C. M., Swetzes, C., Jones, M., Macy, R., Kalichman, M. O., et al. (2009). A simple single-item rating scale to measure medication adherence: further evidence for convergent validity. Journal of the International Association of Physicians in AIDS Care (Chicago, Ill. : 2002), 8, 367-374. crossref(new window)

11.
Kim, J. H., Kim, G. S., Kim, E. J., Park, S., Chung, N., & Chu, S. H. (2011). Factors affecting medication adherence and anticoagulation control in Korean patients taking warfarin. The Journal of Cardiovascular Nursing, 26, 466-474. crossref(new window)

12.
Lee, T. K., Park, I. Y., & Lee, H J. (2010). Goodness of multimedia test program for assessing basketball knowledge. The Korean Journal of Measurement and Evaluation in Physical Education and Sport Science, 12(2), 13-29.

13.
McCormack, P. M., Stinson, J. C., Hemeryck, L., & Feely, J. (1997). Audit of an anticoagulant clinic: doctor and patient knowledge. Irish Medical Journal, 90, 192-193.

14.
Moran, S. M., Fitzgerald, N., Pope, M., Madden, M., & Vaughan, C. J. (2011). Warfarin anticoagulation: a survey of patients' knowledge of their treatment. Irish Journal of Medical Science, 180, 819-822. crossref(new window)

15.
Morisky, D. E., Green, L. W., & Levine, D. M. (1986). Concurrent and predictive validity of a self-reported measure of medication adherence. Medical Care, 24(1), 67-74. crossref(new window)

16.
Poli, D. F., Beck, C. T., & Owen, S. V. (2007). Focus on research methods: Is the CVI an acceptable indicator of content validity? Appraisal and recommendations. Research in Nursing & Health, 30, 459-467. crossref(new window)

17.
Samsa, G., Matchar, D. B., Dolor, R. J., Wiklund, I., Hedner, E., Wygant, G., et al. (2004). A new instrument for measuring anticoagulation-related quality of life: development and preliminary validation. Health and Quality of Life Outcomes, 2, 11-22. crossref(new window)

18.
Siebenhofer, A., Rakovac, I., Kleespies, C., Piso, B., & Didjurgeit, U. (2008). Self-management of oral anticoagulation reduces major outcomes in the elderly. A randomized controlled trial. Thrombosis and Haemostasis, 100, 1089-1098.

19.
Tang, E. O., Lai, C. S., Lee, K. K., Wong, R. S., Cheng, G., & Chan, T. Y. (2003). Relationship between patients' warfarin knowledge and anticoagulation control. The Annals of Pharmacotherapy, 37(1), 34-39. crossref(new window)

20.
The Joint Commission (2011 January 1). Accreditation program: ambulatory care: National Patient Safety Goals. Retrieved January 12, 2012, from http://www.jointcommission.org/assets/1/6/2011_NPSGs_AHC.pdf.

21.
Van Damme, S., Van Deyk, K., Budts, W., Verhamme, P., & Moons, P. (2011). Patient knowledge of and adherence to oral anticoagulation therapy after mechanical heart-valve replacement for congenital or acquired valve defects. Heart & Lung : The Journal of Critical Care, 40 (2), 139-146. crossref(new window)

22.
Winans, A. R., Rudd, K. M., & Triller, D. (2010). Assessing anticoagulation knowledge in patients new to warfarin therapy. The Annals of Pharmacotherapy, 44, 1152-1157. crossref(new window)

23.
Wu, J. R., Chung, M., Lennie, T. A., Hall, L. A., & Moser, D. K. (2008). Testing the psychometric properties of the medication adherence scale in patients with heart failure. Heart & lung : The Journal of Acute and Critical Care, 37, 334-343. crossref(new window)

24.
Yasaka, M., Naritomi, H., & Minematsu, K. (2006). Ischemic stroke associated with brief cessation of warfarin. Thrombosis Research, 118, 290-293. crossref(new window)

25.
Zeolla, M. M., Brodeur, M. R., Dominelli, A., Haines, S. T., & Allie, N. D. (2006). Development and validation of an instrument to determine patient knowledge: the oral anticoagulation knowledge test. The Annals of Pharmacotherapy, 40, 633- 638. crossref(new window)