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Virucidal efficacy of a fumigant containing orth-phenylphenol against classical swine fever virus and porcine reproductive and respiratory syndrome virus
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 Title & Authors
Virucidal efficacy of a fumigant containing orth-phenylphenol against classical swine fever virus and porcine reproductive and respiratory syndrome virus
Cha, Chun-Nam; Park, Eun-Kee; Jung, Ji-Youn; Yoo, Chang-Yeul; Kim, Suk; Lee, Hu-Jang;
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In this study, the virucidal efficacy of a fumigant containing 20% ortho-phenylphenol against classical swine fever virus (CSFV) and porcine reproductive and respiratory syndrome virus (PRRSV) was examined. After each carrier deposited with CSFV and PRRSV suspensions was exposed to the fumigant in a test room for 15 h, all carriers were neutralized and diluted, and each diluted suspension was inoculated into each proper cell line. After incubation, CSFV and PRRSV viability in each cell line was examined and 50% tissue culture infectious dose was calculated. In the results, the concentration of viable virus in all of pathogen control-carriers was more than , and there were no cytotoxicity in all of toxicity control-carriers. In addition, the fumigant inactivated of both CSFV and PRRSV. These findings will be useful for preventing the spread of CSFV and PRRSV infection.
Fumigation;Ortho-phenylphenol;Classical swine fever virus;Porcine reproductive and Respiratory syndrome virus;Virucidal efficacy;
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국가동물방역통합시스템 (KAHIS). 2016. 법정가축전염병발생현황.

국립축산과학원. 2010. 양돈농장 HACCP 관리기준서 - 비육돈 사육농장. 국립축산과학원, 완주. pp. 23-27.

농림축산검역본부. 2016a. 동물약품 - 구제역바이러스 효력 인정 소독제 품목 허가현황.

농림축산검역본부. 2016b. 동물약품 - 조류인플루엔자바이러스 효력 인정 소독제 품목 허가현황.

송주호, 우병준, 허덕, 박선일. 2006. 가축질병의 경제적 영향 분석. 한국농촌경제연구원, 나주. pp. 53-54.

이오형. 2007. 양돈장의 소독 실태와 효과적인 소독방법. 월간양돈.

정필수. 2012. 양돈장 방역위생관리. 방역위생 6: 24-29.

Animal and Plant Quarantine Agency (QIA). 2013. The guideline of the efficacy test for disinfectants. QIA Regulation No. 2013-24. QIA, Anyang, Korea.

Cavanagh D. 1997. Nidovirales: a new order comprising Coronaviridae and Arteriviridae. Arch Virol 142: 629-633.

Cha CN, Cho Y, Lee HJ. 2014. Sporicidal efficacy of a fumigation disinfectant composited to ortho-phenylphenol against spores of Clostridium perfringens. J Fd Hyg Safety 29: 217-222. crossref(new window)

Cha CN, Park EK, Choi H, Kim Y, Yoo CY, Kim S, Lee HJ. 2013. Bactericidal efficacy of Fumagari $OPP^{(R)}$, fumigant against Staphylococcus aureus. J Fd Hyg Safety 28: 349-353. crossref(new window)

Charerntantanakul W. 2012. Porcine reproductive and respiratory syndrome virus vaccines: Immunogenicity, efficacy and safety aspects. World J Virol 1: 23-30. crossref(new window)

Choi EJ, Lee CH, Song JY, Song HJ, Park CK, Kim B, Shin YK. 2013. Genetic diversity of porcine reproductive and respiratory syndrome virus in Korea. J Vet Sci 14: 115-124. crossref(new window)

Christianson WT, Joo HS. 1994. Porcine Reproductive and Respiratory Syndrome: a review. Swine Health Prod 2: 10-28.

Dee SA, Deen J. 2006. Evaluation of an industry-based sanitation protocol for transport vehicles contaminated with porcine reproductive and respiratory syndrome virus. J Swine Health Prod 14: 126-132.

Dee SA, Joo HS. 1994. Prevention of the spread of porcine reproductive and respiratory syndrome virus in endemically infected pig herds by nursery depopulation. Vet Rec 135: 6-9. crossref(new window)

de Smit AJ, Bouma A, de Kluijver EP, Terpstra C, Moormann RJ. 2000. Prevention of transplacental transmission of moderate-virulent classical swine fever virus after single or double vaccination with an E2 subunit vaccine. Vet Q 22: 150-153. crossref(new window)

Edwards S. 2000. Survival and inactivation of classical swine fever virus. Vet Microbiol 73: 175-181. crossref(new window)

Gluhchev G, Ignatov I, Karadzhov S, Miloshev G, Ivanov N, Mosin O. 2015. Studying the virucidal and biocidal effects of electrochemically activited anolyte and catholyte types of water on classical swine fever virus (CSF) and bactrerium E. coli DH5. J Med Physiol Biophys 13: 1-18.

Haas B, Ahl R, Bohm R, Strauch D. 1995. Inactivation of viruses in liquid manure. Rev Sci Tech 14: 435-445. crossref(new window)

Hao X, Shen Z, Wang J, Zhang Q, Li B, Wang C, Cao W. 2013. In vitro inactivation of porcine reproductive and respiratory syndrome virus and pseudorabies virus by slightly acidic electrolyzed water. Vet J 197: 297-301. crossref(new window)

Heckert RA, Best M, Jordan LT, Dulac GC, Eddington DL, Sterritt WG. 1997. Efficacy of vaporized hydrogen peroxide against exotic animal viruses. Appl Environ Microbiol 63: 3916-3918.

Holtkamp DJ, Kliebenstein J, Neumann E, Zimmerman J, Rotto H, Yoder T, Wang C, Yeske P, Mowrer C, Haley C. 2013. Assessment of the economic impacts of porcine reproductive and respirartory syndrome virus on United States pork producers. J Swine Health Prod 21: 72-84.

Hur BH, Lee JW, Song HJ. 2012. Prevalence of major legal communicable diseases in bovine and swine in Jeonbuk province (2004-2008). Korean J Vet Serv 35: 139-145. crossref(new window)

Kang HW, Oh Y, Song JY, Choi EJ. 2014. Survey of porcine reproductive and respiratory syndrome (PRRS) on pig farms in Andong and Hapcheon region. Korean J Vet Serv 37: 11-18. crossref(new window)

Kärber G. 1931. Beitrag zur kollektiven Behandlung pharmakologischer Reihenversuche. Arch Exp Pathol Pharmakol 162: 480-487. crossref(new window)

Krug PW, Lee LJ, Eslami AC, Larson CR, Rodriguez L. 2011. Chemical disinfection of high-consequence transboundary animal disease viruses on nonporous surfaces. Biologicals 39: 231-235. crossref(new window)

Lee OS, Tark D, Yang D, An S, Jun M. 2009. Alterations of peripheral blood mononuclear cells in piglets inoculated with LOM-850 classical swine fever virus vaccine via the intraocular or intranasal routes. Kor J Vet Publ Hlth 33: 27-37.

Lim SI, Son JS, Kim JJ, Cho IS, Kim BH. 2009. Assessment on efficacy of single inoculation of classical swine fever vaccine (LOM) at 90-day-old piglets. Kor J Vet Publ Hlth 33: 235-243.

Mengeling WL, Packer RA. 1969. Pathogenesis of chronic hog cholera. Am J Vet Res 30: 409-417.

Meyers G, Thiel HJ. 1996. Molecular characterization of pestiviruses. Adv Virus Res 47: 53-118. crossref(new window)

Mishra S, Kr. Saini M, Kr. Singh M, Alam S, Raza SK, Thakur LK, Mukharjee S. 2015. Method development and validation for identification of 2-phenyl phenol in siapton 10 liter by gas chromatography mass spectrometry. WJPPS 4: 783-792.

Park EK, Lee SU, Cho KY, Kim Y, Yoo CY, Kim S, Lee HJ. 2014. Fungicidal efficacy of a fumigation disinfectant with ortho-phenylphenol as an active ingredient against Trichophyton mentagrophytes, Candida albicans and Aspergillus niger. J Environ Health Sci 40: 255-263.

Rajbongshi G, Barman NN, Das SK. 2011. Survival and inactivation of classical swine fever virus isolated from pigs of Asom, India. Indian J Anim Sci 81: 330-333.

Shirai J, Kanno T, Tsuchiya Y, Mitsubayashi S, Seki R. 2000. Effects of chlorine, iodine, and quaternary ammonium compound disinfectants on several exotic disease viruses. J Vet Med Sci 62: 85-92. crossref(new window)

Szent-Ivanyi T. 1984. Classical swine fever : new control and eradication methods. Rev Sci Tech Off Int Epiz 3: 465-486. crossref(new window)

Van Oirschot JT. 1999. Classical swine fever (hog cholera). In: Straw BE, D'Allaire S, Mengeling WL, Taylor DJ (8th Ed.), Disease of swine. Iowa State University Press, Iowa. IA, USA. pp. 159-172.

Wills RW, Zimmerman JJ, Yoon KJ, Swenson SL, Hoffman LJ, McGinley MJ, Hill HT, Platt KB. 1997. Porcine reproductive and respiratory syndrome virus: routes of excretion. Vet Microbiol 57: 69-81. crossref(new window)

World Organization for Animal Health (OIE). 2016. List of CSF free Member Counties.

Yoon YD, Kim WI. 2013. Effects of ozone, ultraviolet and an organic acid-based disinfectant against porcine reproductive and respiratory syndrome virus. Korean J Vet Serv 36: 157-162. crossref(new window)

Zimmerman JJ, Yoon KJ, Wills RW, Swenson SL. 1997. General overview of PRRSV: a perspective from the United States. Vet Microbiol 55: 187-196. crossref(new window)