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Induction of Demyelination by Infection of Semliki Forest Virus
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 Title & Authors
Induction of Demyelination by Infection of Semliki Forest Virus
Kim, Hyun Joo; Choi, Chang-Shik; Hong, Seong-Karp;
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 Abstract
Schwann cells and neuronal cells from dorsal root ganglion (DRG) in embryos of rat were cultured in vitro respectively. The purified neuronal cells with anti-mitotic agents and purified Schwann cells were co-cultured and then accomplished myelination processing. Infection of Semliki forest virus into this myelinated co-culture system was performed and then accomplished demyelination. We identified myelination and demyelination processing using antibody of neuropeptide Y.
 Keywords
demyelination;myelination neuropeptide Y;Semliki Forest virus;
 Language
English
 Cited by
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