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A Study on Surface Modification of Nanorod Electrodes for Highly Sensitive Nano-biosensor
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  • Journal title : Applied Chemistry for Engineering
  • Volume 27, Issue 2,  2016, pp.185-189
  • Publisher : The Korean Society of Industrial and Engineering Chemistry
  • DOI : 10.14478/ace.2016.1009
 Title & Authors
A Study on Surface Modification of Nanorod Electrodes for Highly Sensitive Nano-biosensor
Lee, Seung Jun;
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 Abstract
Among many kinds of bioaffinity sensors, the avidin-biotin system has been widely used in a variety of biological applications due to the specific and high affinity interaction of the system. In this work, gold nanorods with high surface area were explored as electrodes in order to amplify the signal response from the avidin-biotin interaction which can be further utilized for avidin-biotin biosensors. Electrochemical performance of electrodes modified with nanorods and functionalized with avidin in response to interactions with biotin at various concentrations using couple as the redox probe were investigated using cyclic voltammetry (CV) and electrochemical impedance spectroscopy (EIS). A very low biotin concentration of less than 1 ng/mL could be detected using the electrodes modified with nanorods.
 Keywords
nano/biosensor;avidin/biotin;surface modification;
 Language
Korean
 Cited by
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