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Effect of β-glucan on immune parameters in the Manila clam Ruditapes philippinarum
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  • Journal title : The Korean Journal of Malacology
  • Volume 31, Issue 2,  2015, pp.123-127
  • Publisher : The Malacological Society of Korea
  • DOI : 10.9710/kjm.2015.31.2.123
 Title & Authors
Effect of β-glucan on immune parameters in the Manila clam Ruditapes philippinarum
Nam, Ki-Woong; Park, Kyung-il;
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-Glucan is a polysaccharide that is widely used as an adductive in fish feed to facilitate immune stimulation. This study aimed to investigate the effect of -glucan on immune responses in the Manila clam Ruditapes philippinarum. For this purpose, three groups of R. philippinarum were exposed to 0%, 0.1%, or 1% -glucan in sea water for 1 hr/day for 2 weeks using an immersion method. Thereafter, two immune parameters-phagocytic rate and antibacterial activity-were measured. R. philippinarum exposed to 1% -glucan showed an approximate 30% significant increase in phagocytic rate. In addition, -glucan significantly limited the growth of the pathogenic bacteria Vibrio tapetis, V. parahaemolyticus, and V. ordalii. Moreover, the mortality rates of -glucan-treated clams decreased during a 17-day experiment. Our study suggests that treatment with -glucan significantly increases the immune responses in R. philippinarum, and that immersion is a simple and effective method for immune stimulation in this species.
-lucan;Ruditapes philippinarum;immune stimulation;antibacterial activity;
 Cited by
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