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Worker Health Hazard and Risk Assessment of Formamide using in Workplaces in South Korea
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 Title & Authors
Worker Health Hazard and Risk Assessment of Formamide using in Workplaces in South Korea
Kim, Hyeon-Yeong;
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 Abstract
Formamide is a colorless fluid with ammonia odor, and irritable when inhaled. It has value of > 5,577 mg/kg in rats for acute oral toxicity and NOAEL of 113 mg/kg/day for target organ (liver) of whole body toxicity. It is also known as reproductive toxicant (1B) and TWA(Time Weighted Average) for it is 10 ppm. Workplace measurements of work places dealing with formamide showed the ppm of all 25 samples was very lower than WEL. However, the exposure concentration can change, depending on workplace condition such as the intensity of work, operating local ventilation system, and wearing protection equipment (Respirators). Therefore, considering it with the risk of whole body toxicity and reproductive toxicity, exposure quantity of each imaginary scenario was calculated at 5.16, 1.72, and . The average value was calculated at 0.02-0.58, 0.02-0.66 at 90 percent of cumulative distribution, 0.02-0.69 at 95 percent of cumulative distribution. Therefore, it was generally evaluated to be safe because all values were below 1. However, caution is required to prevent health hazard because it has hepatotoxicity and reproductive toxicity and risk of a high level momentary exposure, depending on the condition of workplace.
 Keywords
formamide;hazards;risk assessment;dose-response;
 Language
Korean
 Cited by
 References
1.
Kim, C. N., No, J. H., Woen, J. W. et al., Risk Assessment of Toxic Chemicals, OSHRI, (2011)

2.
Ministry of Employment and Labor, Occupational health and safety statute book, Ministry of Employment and Labor, (2015)

3.
KOSHA, Workplace Survey, Korea Occupational Safety & Health Agency, (2009)

4.
Environment Chemical Management Center, Research chemicals in circulation, Ministry of Environment, (2010)

5.
KOSHA, Material Safety Data Sheet(MSDS), Korea Occupational Safety & Health Agency, (2016)

6.
OECD, Screening Information Data Set (SIDS) high production volume chemicals. Nairobi, Kenya: Organisation for Economic Co-operation and Development (OECD); United Nations Environment Programme (UNEP), (2015)

7.
NTP, Technical protocol for sperm morphology and vaginal cytology evaluations in toxicity testing for rats and mice, 10/31/82 version (updated March 1985).Washington, DC: National Toxicology Program (NTP); National Institutes of Health; Public Health Service; U.S. Department of Health and Human Services, (1985)