Publisher : The Korean Society of Environmental Agriculture
DOI : 10.5338/KJEA.2011.30.2.196
Title & Authors
Pharmacokinetic Characterization of Nano-emulsion Vitamin A, D and E (LaVita) in Rats Lee, Young-Ju; Kwon, Min; Kim, Tae-Hwan; Kim, Kyun; Jeong, Sang-Hee; Chang, Hee-Ra;
BACKGROUND: Bioavailability enhancement by solubilization of lipophilic drugs in nano-emulsion has been reported and it may be useful in pharmaceutical and nutraceutical products. This study was performed to compare in vivo bioavailability of nano-emulsion formulation with that of the general product as control. METHODS AND RESULTS: The pharmacokinetics assessment of Vitamin A, D and E complex of nanoemulsion formulation (LaVita), in comparison to the general product, was performed in the male rat plasma by a single oral dose at 20 mL/kg body weight (n
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