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Effect of pH-dependent Solubility on Release Behavior of Alginate-Chitosan Blend Containing Activated Carbon
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  • Journal title : Carbon letters
  • Volume 10, Issue 3,  2009, pp.208-212
  • Publisher : Korean Carbon Society
  • DOI : 10.5714/CL.2009.10.3.208
 Title & Authors
Effect of pH-dependent Solubility on Release Behavior of Alginate-Chitosan Blend Containing Activated Carbon
Oh, Ae-Ri; Jin, Dong-Hwee; Yun, Ju-Mi; Lee, Young-Seak; Kim, Hyung-Il;
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Alginate-chitosan blend containing coconut-based activated carbon was prepared as a drug delivery carrier in order to improve the loading and releasing capacity of the drug. The activated carbon was incorporated as effective adsorbent for drug due to the extremely high surface area and pore volume, high adsorption capacity, micro porous structure and specific surface activity. Alginate-chitosan blend containing coconut-based activated carbon showed the sustained release for a longer period. Alginate-chitosan blend showed higher release of drug as the pH increased and higher release of drug as the content of chitosan decreased due to the pH-dependent solubility of blend components.
Controlled release;pH-dependent solubility;Alginate;Chitosan;Activated carbon;
 Cited by
Electro-responsive Transdermal Drug Release of MWCNT/PVA Nanocomposite Hydrogels,;;;;

Carbon letters, 2010. vol.11. 3, pp.211-215 crossref(new window)
Skirtach, A. G.; Shchukin, D. G.; Sukhorukov, G. B. Langmuir 2004, 20, 6988. crossref(new window)

Lakshmi, S. N.; Cato, T. L. Prog. Polym. Sci. 2007, 32, 762. crossref(new window)

Bostman, O.; Pihlajamaki, H. Biomaterials 2000, 21, 2615. crossref(new window)

Pathiraja, G.; Roshan, M.; Raju, A. Biotechnology Annual Review 2006, 12, 301. crossref(new window)

Shum, H. C.; Kim, J.; Weitz, D. A. J. Am. Chem. Soc. 2008, 130, 9543. crossref(new window)

Xu, Y.; Zhan, C.; Fan, L.; Wang, L.; Zheng, H. Int. J. Pharm. 2007, 336, 329. crossref(new window)

Huang, Y.; Chung, T.; Tzeng, T. Int. J. Pharm. 1999, 182, 93. crossref(new window)

Thaned, P.; Satit, P. Int. J. Pharm. 2007, 331, 61. crossref(new window)

Almeida, P. F.; Almeida, A. J. J. Controll. Release 2004, 97, 431. crossref(new window)

Paul, D. V.; Bart, D. H.; Reinout, V. S. Biomaterials, 1997, 18, 273. crossref(new window)

Olav, G.; Olav, S.; Gudmund, S. Biomaterials 1998, 19, 1815. crossref(new window)

Becheran-Maron, L.; Peniche, C.; Arguelles-Monal, W. Int. J. Biol. Macromol. 2004, 34, 127. crossref(new window)

Sinha, V. R.; Singla, A. K.; Wadhawan, S.; Kaushik, R.; Kumria, R.; Bansal, K.; Dhawan, S. Int. J. Pharm. 2004, 274, 1. crossref(new window)

Martinac, A.; Filipovi, J.; Voinovich, D.; Perissutti, B.; Franceschinis, E. Int. J. Pharm. 2005, 291, 69. crossref(new window)

Beate, T.; Per, B.; Terje, E.; Olav, S.; Patrick, S.; Gudmund, S. Biomaterials 1996, 17, 1069. crossref(new window)

Miyazaki, S.; Nakayama, A.; Oda, M.; Takada, M.; Attwood, D. Int. J. Pharm. 1995, 118, 257. crossref(new window)

Anson, M.; Marchese, J.; Garis, E.; Ochoa, N.; Pagliero, C. J. Membrane Sci. 2004, 243, 19. crossref(new window)

Ballinas, L.; Torras, C.; Fierro, V.; Garcia-Valls, R. J. Phys. Chem. Solids 2004, 65, 633. crossref(new window)