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Extraction of Genistein from Sophora flavescens with Supercritical Carbon Dioxide
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  • Journal title : Korean Chemical Engineering Research
  • Volume 53, Issue 4,  2015, pp.445-449
  • Publisher : The Korean Institute of Chemical Engineers
  • DOI : 10.9713/kcer.2015.53.4.445
 Title & Authors
Extraction of Genistein from Sophora flavescens with Supercritical Carbon Dioxide
Han, Chang-Nam; Kang, Choon-Hyoung;
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 Abstract
This study was directed to finding an optimum extraction condition of genistein from the S. flavescens with supercritical carbon dioxide as a solvent. In this effort, effects of the extraction conditions including pressure, temperature and a co-solvent on the extraction efficiency were investigated. The aqueous ethanol and methanol solutions were used as co-solvents while the tested operating pressure and temperature ranges were from 200 bar to 300 bar and from 308.15 K to 323.15 K, respectively. The concentration of genistein was determined by means of HPLC equipped with a UV detector. From the results, it was observed that an increase in pressure led to the higher extraction efficiency. Further, methanol showed better performance as a co-slovent than ethanol. The DPPH radical scavenging activities were measured to compare antioxidant activities of S. flavescens extracts.
 Keywords
Genistein;S. flavescens;Supercritical Extraction;Co-solvent;Radical Scavenging Activity;
 Language
Korean
 Cited by
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