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A Study on Performance Improvement of Glucose Sensor Adopting a Catalyst Using New Cross Liker
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  • Journal title : Korean Chemical Engineering Research
  • Volume 53, Issue 6,  2015, pp.802-807
  • Publisher : The Korean Institute of Chemical Engineers
  • DOI : 10.9713/kcer.2015.53.6.802
 Title & Authors
A Study on Performance Improvement of Glucose Sensor Adopting a Catalyst Using New Cross Liker
Chung, Yongjin; Kwon, Yongchai;
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 Abstract
In this study, we synthesized a new biocatalyst consisting of glucose oxidase (GOx), polyethyleneimine (PEI) and carbon nanotube (CNT) with addition of terephthalaldehyde (TPA) (TPA/GOx/PEI/CNT) for fabrication of glucose sensor that shows improved sensing ability and stability compared with that using other biocatalysts. Main bonding of the new TPA/GOx/PEI/CNT catalyst is formed by Aldol condensation reaction of functional end groups between GOx/PEI and TPA. Such formed bonding structure promotes oxidation reaction of glucose. Catalytic activity of TPA/GOx/PEI/CNT is evaluated quantitatively by electrochemical measurements. As a result of that, large sensitivity value of is gained. Regarding biosensor stability of TPA/GOx/PEI/CNT catalyst, covalent bonding formed between GOx/PEI and TPA prevents GOx molecules from becoming leaching-out and contributes improvement in biosensor stability. With estimation of the biosensor stability, it is found that the TPA/GOx/PEI/CNT catalyst keeps 94.6% of its initial activity even after three weeks.
 Keywords
Glucose Oxidase;Glucose Sensor;Terephthalaldehyde;Cross Linker;
 Language
Korean
 Cited by
1.
Highly sensitive glucose biosensor using new glucose oxidase based biocatalyst, Korean Journal of Chemical Engineering, 2017, 34, 11, 2916  crossref(new windwow)
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