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A Study on Performance Improvement of Glucose Sensor Adopting a Catalyst Using New Cross Liker
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  • Journal title : Korean Chemical Engineering Research
  • Volume 53, Issue 6,  2015, pp.802-807
  • Publisher : The Korean Institute of Chemical Engineers
  • DOI : 10.9713/kcer.2015.53.6.802
 Title & Authors
A Study on Performance Improvement of Glucose Sensor Adopting a Catalyst Using New Cross Liker
Chung, Yongjin; Kwon, Yongchai;
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In this study, we synthesized a new biocatalyst consisting of glucose oxidase (GOx), polyethyleneimine (PEI) and carbon nanotube (CNT) with addition of terephthalaldehyde (TPA) (TPA/GOx/PEI/CNT) for fabrication of glucose sensor that shows improved sensing ability and stability compared with that using other biocatalysts. Main bonding of the new TPA/GOx/PEI/CNT catalyst is formed by Aldol condensation reaction of functional end groups between GOx/PEI and TPA. Such formed bonding structure promotes oxidation reaction of glucose. Catalytic activity of TPA/GOx/PEI/CNT is evaluated quantitatively by electrochemical measurements. As a result of that, large sensitivity value of is gained. Regarding biosensor stability of TPA/GOx/PEI/CNT catalyst, covalent bonding formed between GOx/PEI and TPA prevents GOx molecules from becoming leaching-out and contributes improvement in biosensor stability. With estimation of the biosensor stability, it is found that the TPA/GOx/PEI/CNT catalyst keeps 94.6% of its initial activity even after three weeks.
Glucose Oxidase;Glucose Sensor;Terephthalaldehyde;Cross Linker;
 Cited by
글루코스 기반 바이오연료전지를 위한 다양한 분자량의 폴리에틸렌이민을 이용한 글루코스 산화효소 고정화,안연주;정용진;권용재;

Korean Chemical Engineering Research, 2016. vol.54. 5, pp.693-697 crossref(new window)
Highly sensitive glucose biosensor using new glucose oxidase based biocatalyst, Korean Journal of Chemical Engineering, 2017, 34, 11, 2916  crossref(new windwow)
International Diabetes Federation, "Diabetes Atlas. 2nd ed.," International Diabetes Federation, 17-71(2003).

Yun, K. E., Park, M. J. and Park, H. S., "Lack of Management of Cardiovascular Risk Factors in Type 2 Diabetic Patients," Int. J. Clin. Pract., 61(1), 39-44(2007). crossref(new window)

Bankar, S. B., Bule, M. V., Singhal, R. S. and Ananthanarayan, L., "Glucose Oxidase-an Over View," Biotechnol. Adv., 27, 489-501(2009). crossref(new window)

Rad, A. S., Ardjmand, M., Jahanshahi, M. and Safekordi, A. A., "Self-assembly Electrode Based on Silver Nanoparticle Toward Electrogenerated Chemiluminescence Analysis of Glucose," Korean J. Chem. Eng, 29, 1063-1068(2012). crossref(new window)

Park, H. G., Hwang, U. and Kim, I. H., "Biochemical Engineering, Energy/Environment: Purification Study of Glucose Oxidase from Aspergillus Niger," Korean Chem. Eng. Res., 39, 512-512(2001).

Kim, H., Jeong, N. J., Lee, S. J. and Song, K. S., "Electrochemical Deposition of Pt Nanoparticles on CNTs for Fuel Cell Electrode," Korean J. Chem. Eng., 25, 443-445(2008). crossref(new window)

Yu H. R., Kim J. G., Im, J. S., Bae T. S. and Lee Y. S., "Effects of Oxyfluorination on a Multi-walled Carbon Nanotube Electrode for a High-performance Glucose Sensor," J. Ind. Eng. Chem., 18, 674-679(2012). crossref(new window)

Sheldon, R. A., "Characteristic Features and Biotechnological Applications of Cross-linked Enzyme Aggregates (CLEAs)," Appl. Microbiol. Biotechnol., 92, 467-477(2011). crossref(new window)

Chung, Y., Hyun, K. H. and Kwon, Y., "Fabrication of Biofuel Cell Improved by $\pi$-conjugated Electron Pathway Effect Induced from a new Enzyme Catalyst Employing Terephtalal Dehyde," Nanoscale. Accepted.

Hyun, K. H., Han, S. W., Koh, W.-G. and Kwon, Y., "Fabrication of Biofuel Cell Containing Enzyme Catalyst Immobilized by Layer-by-layer Method," J. Power Sources., 286, 197-203(2015). crossref(new window)

Ramanavicius, A., Kausaite, A. and Ramanaviciene, A., "Biofuel Cell Based on Direct Bioelectrocatalysis," Biosens. Bioelectron., 20, 1962-1967(2005). crossref(new window)

Kaczmarczyk, B., FTIR Study of Conjugation in Selected Aromatic Polyazomethines," J. Mol. Struct., 1048, 179-184(2013). crossref(new window)

Kurihara, T., Oba, N., Mori, Y., Tomaru, S. and Kaino, T., "New Symmetrical Pi-conjugated Molecules Having Large Third-order Optical Nonlinearities," J. Appl. Phys., 70, 17-19(1991). crossref(new window)

Dobrikov, G., "Photoluminescent Effects in Conjugated Polymer Layers," Vacuum, 76, 227-230(2004). crossref(new window)

Xiao, Y., Patolsky, F., Katz, E., Hainfeld, J. F. and Willner, I., "Plugging Into Enzymes': Nanowiring of Redox Enzymes by a Gold Nanoparticle," Science, 299, 1877-1881(2003). crossref(new window)

Zhang, S., Wang, N., Yu, H., Niu, Y. and Sun, C., "Covalent Attachment of Glucose Oxidase to an Au Electrode Modified with Gold Nanoparticles for Use as Glucose Biosensor," Bioelectrochemistry, 67, 15-22(2005). crossref(new window)

Yan, X. B., Chenn, X. J., Tay, B. K. and Khor, K. A., "Transparent and Flexible Glucose Biosensor Via Layer-by-layer Assembly of Multi-wall Carbon Nanotubes and Glucose Oxidase," Electochem Commun, 9, 1269-1275(2007). crossref(new window)

Liu, Q., Lu, X. B., Li, J., Yao, X. and Li, J. H., "Direct Electrochemistry of Glucose Oxidase and Electrochemical Biosensing of Glucose on Quantum Dots/carbon Nanotubes Electrodes," Biosens Bioelectron, 22, 3203-3209(2007). crossref(new window)

Hyun, K., Han, S. W., Koh, W.-G. and Kwon, Y., "Direct Electrochemistry of Glucose Oxidase Immobilized on Carbon Nanotube for Improving Glucose Sensing," International Journal of Hydrogen Energy, 40, 2199-2206(2015). crossref(new window)

Cai, C. and Chen, J., "Direct Electron Transfer of Glucose Oxidase Promoted by Carbon Nanotubes," Analytical biochemistry, 332, 75-83(2004). crossref(new window)

Bahulekar, R., Ayyangar, N. R. and Ponrathnam, S., "Polyethyleneimine in Immobilization of Biocatalysts," Enzyme Microb. Technol., 13, 858-868(1991). crossref(new window)

Xiong, M. P., "Poly(aspartate-g-PEI800), a Polyethylenimine Analogue of Low Toxicity and Gh Transfection Efficiency for Gene Delivery," Biomaterials, 28, 4889-4900(2007). crossref(new window)