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The Anti-inflammatory Effect and DPPH Free Radical Scavenging Capability of Rhizoma drynariae Aqueous Extract
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  • Journal title : Korean Journal of Acupuncture
  • Volume 32, Issue 4,  2015, pp.169-176
  • Publisher : Society for Meridian and Acupoint
  • DOI : 10.14406/acu.2015.026
 Title & Authors
The Anti-inflammatory Effect and DPPH Free Radical Scavenging Capability of Rhizoma drynariae Aqueous Extract
Kim, Yong-Min; Kim, Ee-Hwa;
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 Abstract
Objectives : This study is to investigate the effects of Rhizoma drynariae aqueous extract(RDA) on cell cytotoxicity, Nitric Oxide (NO) and Prostaglandin production and 1,1-diphenyl-2-picryl ghdrazyl(DPPH) free radical scavenging capability. Methods : Cell cytotoxicity was measured by 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide(MTT) assay. The production of NO was measured by Griess assay. The production of was measured by immunoassay. And, the anti-oxidant activity was measured by the DPPH method. Results : Cell cytotoxicity in 50, 100, 200 and RDA did not increase significantly compared to the RDA untreated group. RDA( and ) inhibited NO and production in lipopolysaccharide-stimulated RAW 264.7 cells. RDA had high DPPH free radical scavenging capability. Conclusions : This study indicates that RDA inhibits NO and production in lipopolysaccharide-stimulated RAW 264.7 cells and improve DPPH free radical scavenging capability. RDA may have an anti-inflammation effect and an anti-oxidant activity.
 Keywords
anti-inflammation;anti-oxidant activity;Nitric Oxide;Prostaglandin ;Rhizoma drynariae;
 Language
English
 Cited by
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