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Review of Clinical Research about Herbal Medicine Treatment on Recurrent Respiratory Tract Infection in Children
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 Title & Authors
Review of Clinical Research about Herbal Medicine Treatment on Recurrent Respiratory Tract Infection in Children
Lee, Ji Hong; Lee, Eun Ju; Lee, Bo Ram; Chang, Gyu Tae;
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 Abstract
Objectives The purpose of this study is to investigate recent clinical studies on effect of herbal medicine treatment for recurrent respiratory tract infection in children. Methods We searched some clinical studies about recurrent respiratory tract infection in children from the China Academic Journal (CAJ) of China National Knowledge Infrastructure (CNKI) (January 2011 to December 2015). Results 50 papers were selected from 168 studies. The herbal decoction was main herbal medicine treatment for recurrent respiratory tract infection in children. Commonly used herbs were Atractylodis Rhizoma Alba, Glycyrrhizae Radix, Astragali Radix, Saposhnikovia Radix and Pseudostellariae Radix. Yupingfeng keli was the most frequently used herbal compound. Total effective rate was 66.4-100%, experimental group was significantly higher than control group in 45 papers (P<0.05). Immune index (in 22 papers) and curative effect of TCM syndrome (in 7 papers) were significantly higher than those of control group after treatment (p<0.05). Conclusions Herbal medicine has been shown as an effective treatment on recurrent respiratory tract infection in children. These research results can be utilized in other clinical studies and in treatment of recurrent respiratory tract infection for children.
 Keywords
Herbal medicine;Recurrent respiratory tract infection;Children;
 Language
Korean
 Cited by
 References
1.
Ahn HS. Textbook of Pediatrics. Seoul: Miraen, 2012:633.

2.
Banz K, Schwicker D, Thomas AM. Economic evaluation of immunoprophylaxis in children with recurrent ear, nose and throat infections. Pharmacoeconomics. 1994;6(5):464-77. crossref(new window)

3.
Kim KB, Kim DG, Kim YH, Kim JH, Min SY, Park EJ, Baek JH, Sung HK, Yu SA, Lee SY, Lee JY, Lee HJ, Chang GT, Jung MJ, Chai JW, Cheon JH, Han YJ, Han JK. Hanbangsoacheongsonyeonuihak. Seoul: Ui Sung Dang Publishing Co. 2015:168-9, 173, 320, 326, 334, 346.

4.
Kang MS, Chang GT, Kim JH. A study on chronic or recurrent respiratory syndromes. J Pediatr Korean Med. 2002;16(2):83-99.

5.
Lee SY. An observation of the chief complaints of pediatric outpatients. J Pediatr Korean Med. 2001;15(1):203-16.

6.
Han JK, Kim YH. Health care utilization of pediatrics outpatients in the oriental hospital. J Pediatr Korean Med. 2001;15(2):209.

7.
Gok SY, Jung SK, Lyu SA, Lee SY. Effects of Gagam-Bopyeyangyeongjeon on the lung weakness children. J Pediatr Korean Med. 2010;24(2):88-98.

8.
Wu T. Wenbingtiaobian. Beijing: People's Medical Publishing House. 1994:190-1.

9.
Clinical Evaluation Unit, Pediatric branch of China association for traditional chinese medicine. Guideline on evaluation of new drug of Chinese materia medica for treatment of recurrent respiratory tract infections in Children. Drug Eval Res. 2015;38(3):238-43.

10.
Choi MH, Kim DG, Lee JY. A study of the chief complaint of pediatric outpatients in the Kyung Hee Oriental Medicine hospital. J Pediatr Korean Med. 2010;24(3):121-37.

11.
The Minjok Medicine News. 2012.11.29. Available from: http://www.mjmedi.com/news/articleView.html?idxno=23863

12.
Zhu ZH. Danxixinfa. Beijing: China Medical Science Press. 1481:49.

13.
Kim SC, Kim SH, No SH, Park SD, Park SG, Seo BI, Seo YB, Shin MS, Lee SI, Lee JC, Lee CH, Ju YS, Choi HY. Herbal prescription. Seoul: Yeong Rim Sa Pulishing Co. 1990:356-7.

14.
Korean Intellectual Property Office. 2001 New technology trend report (Immunostimulants). Daejeon: Korean Intellectual Property Office. 2001:17-20.

15.
Bergmann KC. Assessment of the clinical value of using an immunomodulator in respiratory infections. Adv Exp Med Biol. 1995;371B:795-7.

16.
Quo HL. Evaluation of clinical effect of Huaiqihuang Keli on the recurrent respiratory tract infections in the children patients. Clin Med. 2011;31(10):121-2.

17.
Yu F. Clinical observation of Huaiqihuang Keli in treatment of children with recurrent respiratory tract infections. Mod J Intergr Tradit Chin Western Med. 2015;24(8):861-3.

18.
Wang CQ, Ma R, Li XM, Hu SY, Wang LN, Yu JE, Wang XF, Zhu XK, Ding Y, Zhang XL. Clinical research on optimization program of treating recurrent respiratory tract infection (RRTI) in children with Chinese medicine. Chin J Tradit Chin Med Pharmacy. 2012;27(4):1136-9.

19.
Liu S. Clinical research on the treatment of children with recurrent respiratory tract infection in Jiajianyupingfengsan decoction: a report of 34 cases. Northern Med. 2012;9(7):17.

20.
Meng ZF. The clinical observation of spleen weak syndrome of post-infection in children. J Chin Med. 1988;29(5):35-6.

21.
Li YH. Modified Yupingfengsan in treating 43 cases of recurrent respiratory tract infection in children. Western J Tradit Chin Med. 2013;26(6):60-1.

22.
Del-Rio-Navarro BE, Espinosa-Rosales F, Flenady V, Sienra-Monge JJ. Immunostimulants for preventing respiratory tract infection in children (Review). Cochrane Libr. 2006;4:1-2.

23.
Zhang YZ, Tai XT, Chen L. Evaluation of clinical effect of Shashen Yuping decoction on the recurrent respiratory tract infections in the children patients with Qi and Yin deficiency. J Yunnan Univ Tradit Chin Med. 2011;34(6):44-6.

24.
Li SF. Evaluation of clinical effect of Yupingfeng Keli on the recurrent respiratory tract infections. Chin Foreign Med Rese. 2011;9(27):22-3.

25.
Yu HJ. Evaluation of clinical effect of Yupingfeng liquid on the recurrent respiratory tract infections. Strait Pharm J. 2011;23(10):166-7.

26.
Wang ZM. Clinical research on the treatment of children with recurrent respiratory tract infection in Yibiao Guben decoction. Clin J Chin Med. 2011;11(3):14-5.

27.
Xiang CY. Clinical research on the treatment of children with recurrent respiratory tract infection in Jiajianrenshenwuweizi decoction. Guiding J Tradit Chin Med Pharmacy. 2011;17(7):42-3.

28.
Bai T, Li Y. Evaluation of clinical effect of Zhongyaojiehe treatment on the recurrent respiratory tract infections. Asia Pac Tradit Med. 2011;7(11):69.

29.
Lei J, Liu HH. Evaluation of clinical effect of Yupingfeng keli on the recurrent respiratory tract infections. Jiangxi Med J. 2011;46(11):1027.

30.
Feng B, Qi H, Zheng H. Clinical experience of Zheng Qi - zhong on preventing and treating infantile recurrent respiratory infection based on traditional Chinese constitution theory. Chin J Chin Med. 2011;26(12):1443-4.

31.
Zhou HY, Ma HY, Yang MY. Evaluation of clinical effect of Yupingfeng keli on the recurrent respiratory tract infections. Guiding J Tradit Chin Med Pharmacy. 2011;17(3):31-2.

32.
Wang YC, Zhang LJ, Hu GH, Wang MH, Tang XY, Guo H, Shi YM, Chen SF, Shi CC. Evaluation of clinical effect of Shuangbujiuweitang on the recurrent respiratory tract infections and immune modulation. Chin J Chin Mater Med. 2012;37(7):1039-42.

33.
Ceng MP. Evaluation of clinical effect of Baoeernigtang on the recurrent respiratory tract infections. Chin Med Eng. 2012;20(12):144.

34.
Luo WW, Wu LC. Evaluation of clinical effect of Qingxiaofanggan keli on the recurrent respiratory tract infections. J New Chin Med. 2012;44(4):72-3.

35.
Li HF, Song TD. Shenlingbaizhu powder for the treatment of children with recurrent respiratory tract infections randomized controlled clinical study. J Pract Tradit Chin Intern Med. 2012;26(10):22-3.

36.
Xu WM. Traditional Chinese medicine in the treatment of infantile repeated respiratory tract infection: a clinical observation. J Pract Tradit Chin Intern Med. 2012;26(8):33-4.

37.
Wang XQ. Peitushengjinfang for the treatment of children with recurrent respiratory tract infections. Chin J Exp Tradit Med Formulae. 2012;18(3):216-8.

38.
Gu XM, Chen FM, Zhang XY, Wu XC. Perception of recurrent respiratory tract infection by treating with Chinese medicine. Natl Med Frontiers Chin. 2012;7(4):50-1.

39.
Qing YP. Huanglongzhike keli for the treatment of children with recurrent respiratory tract infections. Shanxi Chin Med. 2013;34(8):943-4.

40.
Cui YQ. Song TD. Flavored Yupinfeng powder treatment of infantile repeated respiratory infection and random parallel control study. J Pract Tradit Chin Intern Med. 2013;27(4):29-30.

41.
Yang N, Hu SY, Li XM, Tong C, Wang LP, Zhou ZH. Comparison Yupingfeng capsule with Tongkangpian for the treatment of children with recurrent respiratory tract infections. Liaoning Chin Med. 2013;40(7):1388-90.

42.
Gao Y. Shenqiyiqiyangyin method treatment of infantile repeated respiratory infection of random parallel control study. J Pract Tradit Chin Intern Med. 2013;27(3):24-5.

43.
Hu YS. The clinical observation of Huangqi Guizhi decoction of five ingredients and Shenlingbaizhu granule in treating 63 cases with RRTI. Med Innov Chin. 2013;10(18):144-5.

44.
Kong FY. Bupiyifei method in treating 80 cases with repeated respiratory infection. Shanxi Chin Med. 2013;34(10):1348.

45.
Ou G. Yupingfengsan combined with Shenlingbaizhusan in treating 60 cases with repeated respiratory infection. Neimenggu Chin Med. 2013;22:19-20.

46.
Xu WP. Jianpiyifeifang in treating 40 cases with repeated respiratory infection. J New Chin Med. 2013;445(11):71-3.

47.
Luo P, Wang H. Clinical research on the treatment of children with recurrent respiratory tract infection in Astragalus particles. J Community Med. 2013;11(17):31.

48.
Wu SH, Li XS. Clinical analysis of Clostridium Butyricum powder in treatment of 80 cases of children with recurrent respiratory tract infection. Chin Mod Doctor. 2014;52(13):124-6.

49.
Huo YM. Huaiqihuang keli in treating 278 cases with repeated respiratory infection. Mod Diagn Treatm. 2014;25(13):2936-7.

50.
Xie J, Liu KL, Sheng BP. Clinical study on Guanyin mixture in treating child recurrent respiratory tract infection with lung and spleen Qi deficiency syndrome. J Hunan Univ Chin Med. 2014;34(1):43-6.

51.
Liu Y. Clinical observation of Kanggan granules combined with pidotimod in treatment of children with recurrent respiratory tract infection. J Hubei Univ Chin Med. 2014;16(4):89-90.

52.
Wu FH. Clinical study of 97 cases of recurrent respiratory tract infection prevented with Fuyangjianzhong granule. J Pediatr TCM. 2014;10(5):24-5.

53.
Zhang JP. Sijunzitang in treating 40 cases with repeated respiratory infection. Chin J Ethnomed ethnopharm. 2014;46(1):46.

54.
Yu WB. Curative effect observation of Yupingfeng granule in the treatment of children recurrent respiratory infection. Chin Community Doctors. 2014;30(34):101-3.

55.
He H. Clinical research on treatment of children with recurrent respiratory tract infection by ingredient-altered Buzhongyiqi decoction. Clinl J Chin Med. 2014;18(6):85-6.

56.
Li BK. Xiaokeyin decoction in treatment of children with recurrent respiratory tract infection. Chin Med Pharmacy. 2014;21(4):99-101.

57.
He R. Shenlingbaizhusan Keli in treatment of children with recurrent respiratory tract infection. Henan Tradit Chin Med. 2014;34(5):973.

58.
Ai YH. Qingredaozhifang in treating 138 cases with repeated respiratory infection. Res Intergr Tradit Chin Western Med. 2014;6(6):308-9.

59.
Zhao T. Clinical observation of Buzhongyiqi decoction in treatment of children with recurrent respiratory tract infections. Chin J Clin Ration Drug Use. 2015;8(12):31-2.

60.
Chen S. Clinical observation of strengthening the spleen and stomach method combined with Yupingfeng keli in the treatment of 40 cases of children with recurrent respiratory tract infections of Qi deficiency type. J Pediatr TCM. 2015;11(6):34-5.

61.
Ma CZ, Du P, Gao D. Clinical study of 100 cases of infantile recurrent respiratory infection treated with Jianer Fuzheng formula. World J Integr Tradit Western Med. 2015;10(1):94-6.

62.
Zhang YF. Clinical observation of strengthening the spleen and surface treatment of children with recurrent respiratory tract infection. J Clin Med. 2015;2(10):1895-6.

63.
Wang ZM, Wang MC, Xu HX. The clinical effect of Yigan keli in the treatment of recurrent respiratory tract infection of children (attack stage). J Pediatr TCM. 2015;11(3):9-11.

64.
Xie M, Lu XY. Clinical efficacy of Astragalus particles in treating children recurrent respiratory tract infection of ying-wei disharmony type. J Pediatr TCM. 2015;11(4):20-2.

65.
Ding HL, Che DD. Clinical observation of "Baogen-I Decoction" in treating repeated respiratory tract infection of lung-spleen deficiency in 60 children. Shanghai J TCM. 2015;49(9):43-5.

66.
Chen YY, Han CM. Clinical research of tonify spleen and lung method to improve immunity in children with recurrent respiratory tract infections. J Liaoning Univ TCM. 2015;17(12):162-4.

67.
Wang WY, Liu XL. Clinical observation of Baoerningtang in treating repeated respiratory tract infection. J Sichuan TCM. 2015;33(11):101-2.