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Anti-wrinkle Effect of Morinda citrifolia (Noni) Extracts
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 Title & Authors
Anti-wrinkle Effect of Morinda citrifolia (Noni) Extracts
Lee, Jung-Noh; Kim, Sang-Woo; Yoo, Young-Kyoung; Lee, Ghang-Tai; Lee, Kun-Kook;
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 Abstract
Wrinkle formation is mainly attributed to the environmental factors such as UV rays, air pollution, smoking and stress etc. Especially, UV rays induce premature skin aging which is characterized by deep wrinkle, leathery dryness etc. Recently, researches on the wrinkle formation and its prevention have been the main theme in cosmetics fields. We have studied the various plant extracts having anti-wrinkle effects and finally showed that Noni (Morinda citrifolia) extracts have the efficacy of promoting the type I collagen synthesis in normal human fibroblast, using PICP assay. We purified one active compound from Noni extracts and identified its structure. It was identified as 6,7-Dimethoxy-2H-1-Benzopyran-2-one; scopoletin by IR, Mass analysis. Scopoletin increased collagen synthesis in a dose dependent manner (89.5% at ). In order to verify the anti-aging effectiveness of the cream containing 3% noni extracsts, we performed the in vivo test with some female volunteers for 12 weeks. It reduced the signs of aging, especially face wrinkles. From these results, we conclude that the noni extracts could be used as an useful anti-wrinkle agent.
 Keywords
anti-wrinkle;noni extracts;scopoletin;collagen;morinda citrifolia;
 Language
Korean
 Cited by
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한국식품영양과학회지, 2008. vol.37. 9, pp.1136-1141 crossref(new window)
2.
화장품 소재로서의 노니 추출물에 관한 특성연구,김승희;장혜진;

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