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Inhibitory Effect of Ginkgo biloba Extracts on Melanin Biosynthesis
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 Title & Authors
Inhibitory Effect of Ginkgo biloba Extracts on Melanin Biosynthesis
Kim, Yoon Suk; Lee, Young Hwa; Lee, Jin Young; Yi, Yong sub;
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In this study, we investigated the inhibitory effect on melanin synthesis of Ginkgo biloba seed oil. The results showed 9.96% inhibitory effect scavenging activity on DPPH and showed a value of 1.33 mM of at a concentration of 0.06% in DMSO by using FRAP assay. G. biloba seed oil inhibited tyrosinase activity up tp 37.72% and suppressed the biosynthesis melanin up to 48.02% at 0.06% in B16/F10 mouse melanoma cell. In G. biloba seed oil treated group tyrosinase, TRP-1, TRP-2 and MITF gen expression levels significantly decreased compared to the contral group at a concentration of 0.04% and 0.06%. In conclusion, these results indicated that G. biloba seed oil extract have a good antimelanogenetic effects.
Ginkgo biloba;DPPH activity;melanin;oil;antimelanogenetic;
 Cited by
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