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Study on the Bioactive Characteristics of Morinda citrifolia as a Cosmetic Raw Material
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 Title & Authors
Study on the Bioactive Characteristics of Morinda citrifolia as a Cosmetic Raw Material
Kim, Seung-Heui; JANG, HYE-JIN;
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This study attempted to investigate the possibility of the use of Morinda citrifolia (MC) as a cosmetic ingredient from its physiological activities such as antioxidant activity, cytotoxicity and anti-aging effect. MC is a tropical plant that has been used as traditional polynesian foods and medicines for over two thousand years. It has been reported that this shrub can improve antimicrobial, anti-cancer and anti-inflammatory effects and strengthen an immune system. The in vitro antioxidant activity of MC was performed to see the DPPH scavenging activity by measuring total polyphenol content and total flavonoid content. As a result, a lack of any cytotoxicity was confirmed in human dermal fibroblasts (HDF) cell. When MC extract at a concentration of over was added, MMP-1 expression considerably diminished. In an in vivo test, in addition, cream containing MC extract was prepared and applied to a total of 22 women in their 30 ~ 50s in ages in the morning and in the evening for four weeks. Changes in keratin, melanin index, pore, skin color and wrinkles under the naked eyes were then comparatively measured. Keratin levels slightly increased in the control group but decreased in the experimental group. In addition, wrinkles diminished in the experimental group. This study found that MC extract controls many MMP-1 related mechanisms with great potential for use as a natural ingredient of anti-aging cosmetics.
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H. S. Lee, S. H. Lee, E. J. Kim, and C. H. Jung, Simultaneous analysis of antimicrobial three straight chain 1,2-alkanediols in cosmetics by gas chromatography, J. Soc. Cosmet. Sci. Korea, 40(1), 37 (2014).

J. M. McCord, Oxygen-derived radicals: a link between reperfusion injury and inflammation, Fed. Proc., 46(7), 2402 (1987).

H. I. Oh, H. B. Park, M. S. Ju, S. Y. Jung, and M. S. Oh, Comparative study of anti-oxidant and anti-inflammatory activities between Curcumae longae Radix and Curcumae longae Rhizoma, Korea J. Herbol., 25(1), 83 (2010).

J. S. Yoo, J. T. Hwang, E. S. Yoo, and B. S. Cheun, Study on herbal extract on the Noni (Morinda citriforia), Korean J. Biotechnol. Bioeng., 19(2), 110 (2004).

H. Y. Choi, Master's Thesis Dissertation, Chung Ang Univ., Seoul, Korea (2004).

H. Y. Choi, B. C. Choi, and S. S. Sim, Antioxidant effects of Noni (Morinda citrifolia) extracts treated with HCl and trypsin, Yakhakhoe Chi., 49(5), 411 (2005).

M. Wang, H. Kikuzaki, K. Csiszar, C. D. Boyd, A. Maunakea, S. F. Fong, G. Ghai, R. T. Rosen, N. Nakatani, and C. T. Ho, Novel trisaccharide fatty acid ester identified from the fruits of Morinda citrifolia (Noni), J. Agric. Food. Chem., 47(12), 4880 (1999). crossref(new window)

S. Sang, X. Cheng, N. Zhu, M. Wang, J. W. Jhoo, R. E. Stark, V. Badmaev, G. Ghai, R. T. Rosen, and C. T. Ho, Iridoid glycosides from the leaves of Morinda citrifolia, J. Nat. Prod., 64(6), 799 (2001). crossref(new window)

H. Mori, T. K. Arai, H. Ishii, N. Endo, and K. Fukuda, Effects of 6-ormylpterin, a xanthine oxidase inhibitor and a superoxide scavenger, on production of nitric oxide RAW264.7 macrophages, Biochim. Biophys. Acta., 1474(1), 93 (2000). crossref(new window)

E. Borenfreund and J. A. Puerner, Toxicity determined in vitro by morphological alterations and neutral red absorption, Toxicol. Lett., 24(2), 119 (1985). crossref(new window)

B. H. So, Device evaluation of skin effect, The Journal of Skin Barrier Research, 8(1), 68 (2006).

J. N. Lee, S. W. Kim, Y. K. Yoo, G. T. Lee, and K. K. Lee, Anti-wrinkle effect of Morinda citrifolia (Noni) extracts, J. Soc. Cosmet. Sci. Korea, 32(4), 227 (2006).

E. J. Lee, Master's Thesis Dissertation, Konkuk Univ., Seoul, Korea (2012).

E. J. Kim, Master's Thesis Dissertation, Wonkwang Univ., Iksan, Korea (2009).

E. J. Kim, Master's Thesis Dissertation, Konkuk Univ., Seoul, Korea (2013).

J. W. Chon, H. Y. Kweon, Y. Y. Jo, M. K. Park, Y. H. Son, and H. S. Lee, A study on the development of functional cosmetics using silk-gland powder of silkworm, J. Soc. Cosmet. Sci. Korea, 38(2), 163 (2012).

J. Y. Lee, K. R. Im, T. K. Jung, K. S. Yoon, The inhibitory effects of Alnus japonica steud. Extract on melanogenesis, J. Soc. Cosmet. Sci. Korea, 39(2), (2013).

E. Y. Jo, Master's Thesis Dissertation, Dong-A Univ., Pusan, Korea (2009).

Y. G. Oh, H. Y. Seo, Y. M. Choi, and D. S. Jung, Evaluation of antioxidant activity of the extracts from the aerial parts of Cnidium officinale Makino, Korean J. Med. Crop Sci., 18(6), 373 (2010).

C. H. Woo, Y. W. Eom, M. H. Yoo, H. J. You, H. J. Han, W. K. Song, Y. J. Yoo, J. S. Chun, and J. H. Kim, Tumor necrosis factor-alpha generates reactive oxygen species via a cytosolic hospholipase, J. Biol. Chem., 275(41), 32357 (2000). crossref(new window)

J. Peterson and J. Dwer, Taxonomic classification helps identify flavonoid containing foods on asemiquantitative food frequency question naire, J. Am. Diet. Assoc., 98(6), 682 (1998).

J. H. Choi, E. Y. Lee, J. S. Kim, G. B. Choi, S. G. Jung, Y. S. Ham, D. C. Seo, and J. S. Heo, Physiological activities according to cultivars and parts of ulsan pear, J. Korean Soc. Appo. Biol. Chem., 49(1), 43 (2006).

M. J. Kim. Master's Thesis Dissertation, Konkuk Univ., Seoul, Korea (2013).

M. R. Al-Sereitia, K. M. Abu-Amerb, and P. Sena, Pharmacology of rosemary (Rosmarinus officinalis) and its therapeutic potentials, Indian J. Exp. Biol., 37, 124 (1999).

Y. M. Choi, H. Kim, J. J. Shin, J. M. Park, and J. Lee, The antioxidant activities of the some commercial teas, J. Korean Soc. Food Sci. Nutr., 32(5), 723 (2003). crossref(new window)

J. Kim, C. W. Lee, E. K. Kim, S. J. Lee, N. H. Park, H. S. Kim, H. K. Kim, Y. P. Jang, and J. W. Kim, Inhibition effect of Gynura procumbens extract on UV-B-induced expression in human dermal fibroblasts, J. Ethnopharmacol., 137(1), 427 (2011). crossref(new window)

S. Kang, J. H. Chung, J. H. Lee, G. J. Fisher, Y. S. Wan, E. A. Duell, and J. J. Voorhees, Topical N-acetyl cysteine and genistein prevent ultraviolet-light-induced signaling that leads to photoaging in human skin in vivo, J. Invest. Dermatol., 120(5), 835 (2003). crossref(new window)

M. K. Gwak, H. S. Choi, and J. H. Hong, Extraction procedures for free radical scavenging activity from Noni fruit (Morinda citrifolia), Korean J. Med. Crop Sci., 19(1), 38 (2011). crossref(new window)