Korean Journal of Otorhinolaryngology-Head and Neck Surgery

Korean Society of Otolaryngology-Head and Neck Surgery (대한이비인후과학회)
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Radiologic Diagnosis and Surgical Treatment of Primary Hyperparathyroidism

원발성 부갑상선 기능항진증의 영상진단 및 수술적 접근법

Tae, Kyeong;Lee, Yong-Seop;Kim, Gyeong-Rae;Lee, Hyeong-Seok;Park, Dong-Woo;Park, Yong-Soo;Kim, Dong-Seon;Kim, Tae-Hwa;An, Yu-Heon
태경;이용섭;김경래;이형석;박동우;박용수;김동선;김태화;안유헌

  • Published : 20060000
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Abstract

With the advance in serum chemical analyses, the diagnosis of primary hyperparathyroidism has become more common, and patients without signs or symptoms attributable to the disease have increased. We performed this study to obtain further understanding and more supporting ideas for the diagnosis and treatment of primary hyperparathyroidism. Subjects and Method：A retrospective study of 19 patients with primary hyperparathyroidism who were treated by surgery from march 1999 to June 2005 was performed. Results：Preoperative localization was performed with computerized tomography, ultrasonography and 99mTc-sestamibi scan. A 99mTc-sestamibi scan has an accuracy of 84% and ultrasonography has an accuracy of 67% for parathyroid tumors. Combination of ultrasonography and 99mTc-sestamibi scan had the accuracy of 93%. All patients were treated by surgery. After surgery, serum calcium and intact parathyroid hormone levels returned rapidly to normal. Parathyroid carcinomas were firm in consistency and adhered to the surrounding tissue and thyroid gland. Conclusion：Ultrasonogram and 99mTc-sestamibi scan was effective for preoperative localization of tumor. If parathyroid carcinoma is suspected, the masswith potential local invasion or regional metastasis should be removed with en bloc resection.

Keywords

References

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