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Antioxidant Activity of Seaweed Extracts from Kongsfjorden, an Inlet in the Arctic's Svalbard Archipelago
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  • Journal title : Ocean and Polar Research
  • Volume 31, Issue 2,  2009, pp.213-218
  • Publisher : Korea Institute of Ocean Science & Technology
  • DOI : 10.4217/OPR.2009.31.2.213
 Title & Authors
Antioxidant Activity of Seaweed Extracts from Kongsfjorden, an Inlet in the Arctic's Svalbard Archipelago
Lee, Jung-Im; Kim, You-Ah; Kong, Chang-Suk; Yea, Sung-Su; Han, Tae-Jun; Kang, Sung-Ho; Kim, Jee-Hee; Seo, Young-Wan;
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 Abstract
We examined the intracellular antioxidative effects of 20 Arctic seaweed extracts in Raw 264.7 cells. Each seaweed species was subjected to extraction using acetone/dichloromethane and methanol, respectively, after which the extracts were combined and used as the test sample. The antioxidant ability of all 20 seaweeds extracts was evaluated using four different activity tests, including the degree of occurrence of intracellular reactive oxygen species (ROS), , and lipid peroxidation in Raw 264.7 cells, as well as the extent of oxidative damage of genomic DNA purified from Raw 264.7 cells. Crude extracts from Monostroma obscurum, Alaria esculnta, Laminaria digitata, Desmarestia aculeata, Chorda filum, Ptilota seriata, Phycidrys rubens, Devaleraea ramentacea and Palmaria palmata exhibited significant scavenging effects on the generation of intracellular ROS. Among them, Monostroma obscurum and Phycidrys rubens significantly inhibited membrane lipid peroxidation and DNA oxidation. Moreover, Phycidrys rubens exhibited scavenging effects on peroxynitrite generated from SIN-1.
 Keywords
Arctic seaweeds;antioxidant;reactive oxygen species (ROS);lipid peroxidation;DNA damage;
 Language
Korean
 Cited by
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