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Isolation and Antioxidant Activity of Methyl Aconitates from Arctic Red Alga Polysiphonia stricta
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  • Journal title : Ocean and Polar Research
  • Volume 36, Issue 3,  2014, pp.247-254
  • Publisher : Korea Institute of Ocean Science & Technology
  • DOI : 10.4217/OPR.2014.36.3.247
 Title & Authors
Isolation and Antioxidant Activity of Methyl Aconitates from Arctic Red Alga Polysiphonia stricta
Lee, Jung Im; Kong, Chang-Suk; Baek, Seung Oh; Seo, Youngwan;
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 Abstract
In our continuing study on the antioxidant activity of Polysiphonia stricta, its crude extract was fractionated into n-hexane, 85% aqueous methanol (85% aq.MeOH), n-butanol (n-BuOH), and water fractions according to solvent polarity. The solvent fractions were evaluated for their potential to inhibit lipid peroxidation and reactive oxygen species (ROS) production in HT 1080 cells. The n-BuOH fraction most strongly inhibited both lipid peroxidation and ROS production in HT 1080 cells. The n-BuOH fraction was further separated by repeated silica gel column chromatography and RP-HPLC to give methyl aconitates (2 and 3). The chemical structure of isolated compounds was determinated by NMR spectral analysis.
 Keywords
Polysiphonia stricta;methyl aconitate;antioxidant activity;
 Language
Korean
 Cited by
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