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Teratological Effects of Enrofloxacin on the Embryos and Fetus During the Hatching of Chicken Eggs
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 Title & Authors
Teratological Effects of Enrofloxacin on the Embryos and Fetus During the Hatching of Chicken Eggs
Lee, Jin-Heon; Lee, Ji-Hee; Cho, Y-Eaun;
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The purpose of this study was to investigate the teratological effects of enrofloxacin, a veterinary antibiotic, on the embryos and fetus of hatching chicken eggs. A control group and four experimental fertilized egg groups were set up. The four experimental groups were injected with 0.05 ml, 0.1 ml, 0.2 ml, and 0.3 ml enrofloxacin () respectively. During the hatching period, the weights of total eggs, inside material(yolk and white) and embryos or fetuses, embryo growth, and teratological effects were investigated. In the experimental groups (fertilized eggs injected with 0.05 ml, 0.1 ml, 0.2 ml and 0.3 ml enrofloxacin), the weights of total eggs were decreased, but the yolk and white weights were increased by the higher amount of antibiotics. The weights of embryos (fetuses) in experimental groups were 86.1%, 78.6%, 65.6% and 61.4% of the control, respectively. Retarded growth, deformity and embryo loss were observed in experimental groups. Teratological effects such as undeveloped eyes, wings and legs, and deformed head and bill were also detected. In conclusion, we found that veterinary antibiotics, enrofloxacin have made teratological effects on the embryos and fetus of hatching eggs.
enrofloxacin;embryo;fetus;teratogenic effects;
 Cited by
식품 중 플루오로퀴놀론계 항생제의 분석,김희연;신민수;최희주;박세종;송재상;정소영;최선희;이화정;김영선;최재천;

한국식품과학회지, 2009. vol.41. 6, pp.636-643
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