Advanced SearchSearch Tips
Exposure of Laboratory Workers to Airborne Nanoparticles during Acid Treatments on Engineered Carbon Nanotubes
facebook(new window)  Pirnt(new window) E-mail(new window) Excel Download
 Title & Authors
Exposure of Laboratory Workers to Airborne Nanoparticles during Acid Treatments on Engineered Carbon Nanotubes
Ha, Ju-Hyun; Shin, Yong-Chul; Lee, Seung-Chul; Paik, Samuel Y.; Kim, Boo-Wook; Choi, Byung-Soon; Kang, Dong-Mug; Paik, Nam-Won;
  PDF(new window)
This study was performed to investigate laboratory workers` exposures to airborne nanoparticles at a university laboratory where acid treatment experiments were conducted on the surfaces of engineered carbon nanotubes (CNTs). The surface area concentrations, number concentrations, and mass concentrations of airborne nanoparticles were measured at personal breathing zones (PBZs) for various tasks using direct reading instruments. For all three metrics, airborne nanoparticle concentrations during the experiments were higher than background levels measured before and after the experiments for all three metrics. Among the various tasks that were performed as part of these experiments, one task that involved filtering a mixture of acid and CNTs showed the highest concentrations in all three metrics, with concentrations of /cc, 24320 pt/cc, and , respectively. Nanoparticle surface area concentrations measured at a representative area fluctuated with those at the PBZs in the laboratory. This result indicates that nanoparticles generated during the experiments were not just limited to the PBZs of the workers but were also present throughout the room, potentially exposing co-located workers. CNTs were detected by a transmission electron microscope in an air sample collected while handling the CNTs. All the tasks were performed inside fume hoods, with the sliding sashes open to their required heights. It was noted that the capture velocities of the fume hoods were much lower than the American National Standards Institute (ANSI)`s recommendation level (0.4 to 0.6 m/s). In conclusion, this study showed that, due to inadequate control, laboratory researchers performing acid treatment experiments on surfaces of CNTs were exposed to airborne nanoparticles generated during the tasks.
carbon nanotubes;CNTs;airborne nanoparticle;laboratory;exposure;control;
 Cited by
탄소나노튜브 필름 제조 실험실의 세부작업별 공기 중 나노입자 노출 농도,하주현;신용철;

한국산업보건학회지, 2010. vol.20. 4, pp.248-255
나노물질의 측정전략의 주요 쟁점,윤충식;

한국환경보건학회지, 2011. vol.37. 1, pp.73-79 crossref(new window)
용접 및 연마에서 발생되는 나노입자 특성 평가 : 수농도 및 입경분포 분석,김부욱;김현욱;

한국산업보건학회지, 2012. vol.22. 3, pp.184-190
A Review on Chemical Exposure and Related Health Risks in Laboratory Workers, Korean Journal of Environmental Health Sciences, 2010, 36, 6, 441  crossref(new windwow)
Ministry of Education, Science and Technology (MEST), Ministry of Strategy and Finance(MOSF), Ministry of Knowledge Economy(MKE), Ministry of Environment(ME), Ministry of Construction and Transportation(MOCT) : Korea National Nanotechnology Development Plan, GOVP1200134230, 2001.

Subcommittee on Nanoscale Science, Engineering, and Technology(NEST), Committee on Technology (CT), National Science and Technology Council : The National Nanotechnology Initiative Strategic Plan. National Nanotechnology Coordination Office (NNCO), U.S. Government, Arlington, VA, 2004.

The Royal Society and Royal Academy of Engineering : Nanoscience and Nanotechnologies: Opportunities and Uncertainties. RS Policy Document 19/04, The Royal Society, 113, 2004.

Maynard, A. D. and Michelson, E. : Nanotechnology Consumer Products Inventory. Woodrow Wilson International Center for Scholars, 2005.

Korea Institute of Science & Technology Evaluation and Planning(KISTEP) : Nanotechnology Assessment Report, GOVP1200613138. Ministry of Education, Science and Technology(MEST), 2005.

Oberdorster, G., Sharp, Z., Atudorei, V., Elder, A., Gelein, R., Lunts, A., Kreyling, W. and Cox, C. : Extrapulmonary translocation of ultrafine carbon particles following whole-body inhalation exposure of rats. Journal of Toxicological Environmental Health, 65(20), 1531-1543, 2002. crossref(new window)

Oberdorster, G., Sharp, Z., Atudorei, V., Elder, A., Gelein, R., Kreyling, W. and Cox, C. : Translocation of inhaled ultrafine particles to the brain. Inhalation Toxicology, 16(6-7), 437-445, 2004. crossref(new window)

Kreying, W. G., Semmler, M., Erbe, F., Mayer, P., Takenaka, S., Schulz, H., Oberdoster, G. and Ziesenis, A. : Translocation of ultrafine insoluble iridium particles from lung epithelium to extrapulmonary organs is size dependent but very low. Journal of Toxicological Environment, Health Part A, 65(20), 1513-1530, 2002. crossref(new window)

Maynard, A. D. and Kuempel, E. D. : Airborne nanostructured particles and occupational health. Journal of Nanoparticle Research, 7(6), 587-614, 2005. crossref(new window)

Lam, C. W., James, J. T., McCluskey, R. and Hunter, R. L. : Pulmonary toxicity of single-wall carbon nanotubes in mice 7 and 90 days after intratracheal instillation. Toxicological Sciences, 77(1), 126-134, 2004.

Warheit, D. B., Laurence, B. R., Reed, K. L., Roach, D. H., Reynolds, G. A. M. and Webb, T. R. : Comparative toxicity assessment of single-wall carbon nanotubes in rats. Toxicological Sciences, 77, 117-125, 2004.

Monteiro-Riviere, N. A., Nemanich, R. J., Inman, A. O., Wang, Y. Y. and Riviere, J. E. : Multi-walled carbon nanotube interactions with human epidermal keratinocytes. Toxicology Letters, 155(3), 377-384, 2005. crossref(new window)

Poland, C. A., Duffin, R., Kinloch, I., Maynard, A., Wallace W. A. H., Seaton, A., Stone, V., Brown, S., MacNee, W. and Donaldson, K. : Carbon nanotubes introduced into the abdominal cavity of mice show asbestos-like pathogenicity in a pilot study. Nature Nanotechnology, 3, 423-428, 2008. crossref(new window)

Takagi, A. H., Hirose, A., Nishimura, T., Fukumori, N., Ogata, A., Ohashi, N., Kitajima, S. and Kanno, J. : Induction of mesothelioma in p53+/- mouse by intraperitoneal application of multi-wall carbon nanotube. Journal of Toxicological Sciences, 33(1), 105-116, 2008. crossref(new window)

Maynard, A. D. : Nanotechnology: The next big thing, or much ado about nothing?. The Annals of Occupational Hygiene, 51(1), 1-12, 2006. crossref(new window)

Ku, B. K. and Maynard, A. D. : Comparing aerosol surface-area measurements of monodisperse ultrafine silver agglomerates by mobility analysis, transmission electron microscopy and diffusion charging. Journal of Aerosol Science, 36(9), 1108-1124, 2005. crossref(new window)

Ku, B. K., Maynard, A. D., Baron, P. A. and Deye, G. J. : Observation and measurement of anomalous responses in a differential mobility analyzer caused by ultrafine fibrous carbon aerosols. Journal of Electrostatics, 65, 542-548, 2007. crossref(new window)

Han, J. H., Lee, E. J., Lee, J. H., So, K. P., Lee, Y. H., Bae, G. N., Lee, S. B., Ji, J. H., Cho, M. H. and Yu, I. J. : Monitoring multiwalled carbon nanotube exposure in carbon nanotube research facility. Inhalation Toxicology, 20, 741-749, 2008.

Methner, M., Hodson, L., Dames, A. and Geraci, C. : Nanoparticle emission assessment technique(NEAT) for the identification and measurement of potential inhalation exposure to engineered nanomaterials-Part B: Results from 12 field studies. Journal of Occupational and Environmental Hygiene, 7, 163-176, 2010. crossref(new window)

Kim, Y., Park, J., Kim, H., Lee, J., Bae, E., Lee, S., Kwak, B. K., Choi, K., Park, K. and Yi, J. : Investigation on the main exposure sources of nanomaterials for nanohazards assessment. Journal of Environmental Toxicology, 23(4), 257-265, 2008.

Kang, G. U., Kim, N. S. and Lee, H. J. : Mass concentration and ion composition of size-segregated particulate matter during the non-Asian dust strom of spring 2007 in Iksan. Journal of Environmental Health Sciences, 34(4), 300-310, 2008. crossref(new window)

American Industrial Hygiene Association. ANSI/AIHA Z9.5-2003 American National Standard Laboratory Ventilation. AIHA, Fairfax, VA, 2003.

Methner, M. M., Birch, M. E., Evans, D. and Hoover, M. D. : Health Hazard Evaluation Report 2005-0291-3025. National Institute of Safety and Health, Dept. of Health and Human Services, 2006.

Daigle, C. C., Chalupa, D. C., Gibb, F. R., Morrow, P. E., Oberdster, G., Utell, M. J. and Frampton, M. W. : Ultrafine particle deposition in humans during rest and exercise. Inhalation Toxicology, 15(6), 539-552, 2003. crossref(new window)

Jaques, P. A. and Kim, C. S. : Measurement of total lung deposition of inhaled ultrafine particles in healthy men and women. Inhalation Toxicology, 12(8), 715-731, 2000. crossref(new window)