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Estimation of Humidifier Disinfectant Amounts Inhaled into the Respiratory System
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 Title & Authors
Estimation of Humidifier Disinfectant Amounts Inhaled into the Respiratory System
Park, Dong-Uk; Ryu, Seung-Hun; Lim, Heung-Kyu; Kim, Sun-Kyung; Roh, Hyun-Suk; Cha, Won-Seok; Park, Dooyong;
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In South Korea, many cases of humidifier disinfectant-associated lung injury (HDLI) have been reported among people who used humidifier products containing humidifier disinfectant (HD). The objectives of this study are to estimate both airborne HD concentration in the room where HD was used and the amount of humidifier disinfectant absorbed into the respiratory system. Information and data on the HDs were collected using a structured questionnaire and home environmental investigations include the volume of HD (ml) and hours used per day, concentration of disinfectants contained in the HD brand (), volume of the room (), assumed ventilation rate () and breathing rate assumed (). We used children aged under five years old as a sample and estimated both airborne HD concentrations and amount of HD absorbed into the respiratory system. The estimated airborne concentration of HD in the room ranged from 68 to for PHMG (polyhexamethylene guanidine phosphate) and from 16 to for PGH (oligo (2-(2-ethoxy) ethoxyethyl guanidine). The amount of HD absorbed in the respiratory system per day was estimated to range from 227 to for PHMG and from 53 to for PGH. In conclusion, a great amount of HD was likely absorbed into respiratory system, likely beyond the level of the capacity of the immune system to remove the HD absorbed.
CMIT;humidifier disinfectant (HD);humidifier disinfectant-associated lung injury (HDLI);MIT;PGH;PHMG;
 Cited by
가습기 살균제 폐 손상 피해자의 살균제 노출 특성 -태아와 임산부 노출을 중심으로 -,박동욱;류승훈;임흥규;김선경;안종주;노현석;최예용;차원석;이은;홍상범;도경현;조재림;배문주;신동천;백도명;홍수종;

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