Advanced SearchSearch Tips
Characteristics of Gold and Silver Based Bi- and Tri-metallic SPR Chip in the Intensity Measurement Mode
facebook(new window)  Pirnt(new window) E-mail(new window) Excel Download
 Title & Authors
Characteristics of Gold and Silver Based Bi- and Tri-metallic SPR Chip in the Intensity Measurement Mode
Kim, Hyungjin; Kim, Chang-duk; Sohn, Young-Soo;
  PDF(new window)
Characteristics of the conventional gold (Au) surface plasmon resonance (SPR) chip, bi-metallic(Au/silver (Ag)) SPR chip, and tri-metallic(Au/Ag/Au) SPR chip were investigated and compared in the intensity measurement mode for the enhancement of SPR image sensor reactivity. Reflectance curves of the Au, bi- and tri-metallic SPR chips were acquired in phosphate-buffered saline (PBS) solution and were compared. The line width of the reflectance curve of the bi-metallic chip was the narrowest among the three different types of the chips. Also, the tangential slope of the bi-metallic chip was steeper than those of the other chips. Various concentrations of bovine serum albumin (BSA) were utilized in the SPR experiment. As a result, among the above three chips reflectance variation value of the bi-metallic chip was the largest.
SPR image sensor;Intensity measurement mode;Bi- and tri-metallic SPR chip;
 Cited by
Surface plasmon resonance sensing of a biomarker of Alzheimer disease in an intensity measurement mode with a bimetallic chip, Journal of the Korean Physical Society, 2016, 69, 5, 793  crossref(new windwow)
E.J. Kim, B.H Hun, Sung Su Kim, Sang Jun Lee, "Analysis for new drugs R&D activation", Biotech Policy Research Center, 2010.

K.H. Lee, "The pharmaceutical industry R & D, Present and Future", Korea Pharmaceuticals Association, 2015.

3. on Feb. 10, 2016)

Alvydas Mikulskis, Dave Yeung, Meena Subramanyam, Lakshmi Amaravadi, "Solution ELISA as a platform of choice for development of robust, drug tolerant immunogenicity assays in support of drug development", Journal of Immunological Methods, Vol. 365, pp. 38-49, 2011. crossref(new window)

Mei-Feng Lee, Jing-Yu Chen, Chien-Fang Peng, "Study on the LAMP-PCR-hybridization-thermal melt-ELISA method for molecular detection of multidrug resistance in Mycobacterium tuberculosis isolates", Biomarkers and Genomic Medicine, Vol. 6, pp. 126-132, 2014. crossref(new window)

Yulin Chen, Kohei Nakamoto, Osamu Niwa, and Robert M. Corn, "On-chip synthesis of RNA aptamer microarrays for multiplexed protein biosensing with SPR imaging measurements", Langmuir, Vol. 28, pp. 8281-8285, 2012. crossref(new window)

Jennifer B. Fasoli and Robert M. Corn, "Surface enzyme chemistries for ultrasensitive microarray biosensing with SPR imaging", Langmuir, Vol. 31, pp. 9527-9536, 2015. crossref(new window)

Zhiyou Wang, Zhiqiang Cheng, Vikramjeet Singh, Zheng Zheng, Yanmei Wang, Shaopeng Li, Lusheng Song, and Jinsong Zhu, "Stable and sensitive silver surface plasmon resonance imaging sensor using trilayered metallic structures", Analytical Chemistry, Vol. 86, pp. 1430-1436, 2014. crossref(new window)

Hyungjin Kim, Sung-Youp Lee, Hong Tak Kim, Ki-Won Yang, and Young-Soo Sohn, "Characteristics of gold and silver bimetallic surface plasmon resonance chip in intensity measurement mode and calculation of refractive index using critical angle", Journal of Sensor Science and Technology, Vol. 24, pp. 423-428, 2015. crossref(new window)

Y. K. Lee, K. -S. Lee, W. M. Kim, and Y. -S. Sohn, "Detection of amyloid-${\beta}$42 using a waveguide coupled bimetallic surface plasmon resonance sensor chip in the intensity measurement mode", PLoS ONE, Vol. 9, e98992, 2014. crossref(new window)

E. Kretschmann, H. Raether. "Radiative decay of non-radiative surface plasmons excited by light", Zeitschrift fur Naturforschung A, Vol. 23, pp. 2135-2136, 1968.

Gopa Mandal, Munmun Bardhan, Tapan Ganguly, "Interaction of bovine serum albumin and albumin-gold nanoconjugates with L-aspartic acid. A spectroscopic approach", Colloids and Surfaces B:Biointerfaces, Vol. 81, pp. 178-184, 2010.

Soon Eon Bae, Kwideok Park, and Dong Keun Han, "Surface characteristics and selective albumin adsorption of Si wafer chemisorbed with C18-PEG", Biomaterials Research, Vol. 12, pp. 167-173, 2008.