Advanced SearchSearch Tips
A Study of the Effect on Obesity in Taeeumin Animal-experimental Model Induced Lung Fibrosis with Bleomycin
facebook(new window)  Pirnt(new window) E-mail(new window) Excel Download
 Title & Authors
A Study of the Effect on Obesity in Taeeumin Animal-experimental Model Induced Lung Fibrosis with Bleomycin
Kim, Yoonha; Park, Junghwan; Kwak, Jinyoung; Park, Jungmi; Ahn, Taek won;
  PDF(new window)
Objectives The objective of this study is to develop a taeeumin animal-experimental model induced lung fibrosis with Bleomycin and evaluate the effect on obesity in this animal-experimental model.Methods The subjects were divided into 3 groups : normal group, high fat diet(HFD) control group, and HFD group administered with bleomycin(n
Taeeumin;Obesity;Leptin;Adiponectin;Bleomycin;Animal-experimental model;
 Cited by
Lee JM. Dongeisusebowon. Seoul: Daesungmoonhwasa. 1997;1:5, 4:1,10,29-32. (Korean)

Lee JM. Dongeisusebowon. 2nd rev. Seoul: Yeogang. 2003:36,278. (Korean)

Dept. of Sasang Constitutional Medicine. All colleges of Korean med. in Korea(compilation). The revised and enlarged Sasang Constitutional Medicine. Seoul: Jipmoondang. 2012:131. (Korean)

Lee JH, Lee EJ, Koh BH. A study on the schematic organization of the sub-classification system of the Taeeumin symptomatology. J Sasang Constitut Med. 2011:23(1):63-78. (Korean)

Moon SH, Sin SH, Kim HJ, Kim JY. A relationship of the obesity and body composition analysis by Sasang constitution. J Oriental Rehab Med. 2002;12(4):1-10. (Korean)

Kim DR. A study on 4 type constitution and life character of obese patients. J of Const Med. 1997;9(1): 303-13. (Korean)

Kim DR, Baek TH. Clinical Study on the Relationship of Sasang constitution and Obesity. J Sasang Constitut Med. 1996;8(1):319-35. (Korean)

Ryu SM, Shin SU, Kim KS, Moon JS, Yoon YS. Analysis of obesity degree and comparision of weight control program among Sasang constitution. Journal of Korean Oriental Association for Study of Obesity. 2005;5(1):21-9. (Korean)

Adamson IYR, Bowden DH. The pathogenesis of bleomycin induced pulmonary fibrosis in mice. Am J Pathol. 1974;77:185-97.

Chandler DB, Hyde DM, Gin SN. Morphometric estimates of infiltrative cellular changes during the development of bleomycin-induced pulmonary fibrosis in hamsters. Am J Pathol. 1996;112:981-92.

Vanhee D, Gosset P, Boitelle A, Wallaert B, Tonnel AB. Cytokines and cytokine network in silicosis and coal workers' pneumoconiosis. Eur Respir J 1995.8: 834-42.

Zhang K, Gharaee Kermani M, McGarry B, Remick D, Phan SH. TNF-alpha-mediated lung cytokine networking and eosinophil recruitment in pulmonary fibrosis. J Immunol. 1997;158:954-9.

Huaux F, Lardot C, Arras M, Delos M, Many MC, Coutelier JP, et al. Lung fibrosis induced by silica particles in NMRI mice is associated with an upregulation of the p40 subunit of interleukin-12 and Th-2 manifestations. Am J Respir Cell Mol Biol. 1999;20: 561-72. crossref(new window)

Lee SG, Kwak CK, Lee EJ, Koh BH, Song IB. The study on the upgrade of QSCCII(II);the study on the re-validity of QSCCII. J Sasang Constitut Med. 2003;15:39-50. (Korean)

Pak YS, Kim JS, Lee JH, Lee EJ, Koh BH. Association between Sasang Constitution, Impaired Lung Function and Metabolic Syndrome among Middle-aged Adults in Korea. J Sasang Constitut Med 2013;25(3):180-194. (Korean) crossref(new window)

Muoio DM, Dohm GL. Peripheral metabolic actions of leptin. Best Pract Res Clin Endocrinol Metab. 2002;16(4):653-66. crossref(new window)

Galic S, Oakhill JS, Steinberg GR. Adipose tissue as an endocrine organ. Mol Cell Endocrinol. 2010;316: 129-139. crossref(new window)

Unal M, Eskandari G, Muslu N, Pata YS, Akbas Y. Serum leptin levels in patients with allergic rhinitis. Otolaryngol Head Neck Surg. 2006;134:331-333. crossref(new window)

Guler N, Kirerleri E, Ones U, Tamay Z, Salmayenli N, Darendeliler F. Leptin: does it have any role in childhood asthma? J Allergy Clin Immunol. 2004;114: 254-259. crossref(new window)

Bruno A, Chanez P, Chiappara G, Siena L, Giammanco S, Gjomarkaj M, et al. Does leptin play a cytokine-like role within the airways of COPD patients? Eur Respir J. 2005;26:398-405. crossref(new window)

Guven M, Bulut Y, Aladag I, Yelken K, Erdogan H. Serum leptin levels in patients with nasal polyposis. J Laryngol Otol. 2008;122:590-592. crossref(new window)

Lee SM, Choi HJ, Oh CH, Oh JW, Han JS. Leptin Increases TNF-α Expression and Production through Phospholipase D1 in Raw 264.7 Cells. PLoS One. 2014;9(7):e102373. crossref(new window)

Björnholm M, Münzberg H, Leshan RL, Villanueva EC, Bates SH, Louis GW, et al. Mice lacking inhibitory leptin receptor signals are lean with normal endocrine function. J Clin Invest 2007;117:1354-60. crossref(new window)

Lantz KA, Hart SG, Planey SL, RoitmanMF, Ruiz-White IA, Wolfe HR, et al. Inhibition of PTP1B by Trodusquemine (MSI‐1436) Causes Fat‐specific Weight Loss in Diet‐induced Obese Mice. Obesity (Silver Spring) 2010;18:1517-23. crossref(new window)

Steinberg GR, Smith AC, van Denderen BJW, Chen Z, Murthy S, Campbell DJ, et al. AMP-activated protein kinase is not down-regulated in human skeletal muscle of obese females. J Clin Endocrinol Metab. 2004;89:4575-4580. crossref(new window)

Cintra DE, Ropelle ER, Moraes JC, Pauli JR, Morari J, Souza CT, et al. Unsaturated fatty acids revert diet-induced hypothalamic inflammation in obesity. PLoS One. 2012;7:e30571. crossref(new window)

Ozcan L, Ergin AS, Lu A, Chung J, Sarkar S, Nie D, et al. Endoplasmic reticulum stress plays a central role in development of leptin resistance. Cell Metab. 2009;9:35-51. crossref(new window)

Ziemke F, Mantzoros CS. Adiponectin in insulin resistance: lessons from translational research. Am J Clin Nutr. 2010;91:258S-61S. crossref(new window)

Berg AH, Combs TP, Du X, Brownlee M, Scherer PE. The adipocyte-secreted protein Acrp30 enhances hepatic insulin action. Nat Med. 2001;7(8):947-953. crossref(new window)

Matsuzawa Y. Establishment of a concept of visceral fat syndrome and discovery of adiponectin. Proc Jpn Acad 2010;86:131-140. crossref(new window)

Matsuzawa Y. Adiponectin: Identification, physiology and clinical relevance in metabolic and vascular disease. Atheroscler Suppl. 2005;6:7-14. crossref(new window)

Marceau P, Biron S, Hould FS, Marceau S, Simard S, Kral JG, et al. Liver pathology and the metabolic syndrome X in severe obesity. J Clin Endocrinol Metab. 1999;84(5):1513-1517. crossref(new window)

Brown MS, Goldstein JL. The SREBP pathway: regulation of cholesterol metabolism by proteolysis of a membrane-bound transcription factor. Cell. 1997; 89(3):331-340. crossref(new window)