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Analysis of 2-Mercapro-1-Methylimidazole in Controlling Drug of Thyroid by Differential Pulse Polarography
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 Title & Authors
Analysis of 2-Mercapro-1-Methylimidazole in Controlling Drug of Thyroid by Differential Pulse Polarography
Kim, Il-Kwang; Chun, Hyun-Ja; Han, Sung-Soo;
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 Abstract
The determination of 2-mercapto-1-methyl-imidazole (MMI) in 5.0 M lithium perchlorate suporting electrolyte has been investigated by the differential pulse polarography. The optimum condition of MMI analysis was as follows; -0.9 volts initial potential, 0.08 mV pulse height, 2 mV/sec scan rate, and medium mercury drop size. Standard calibration curve showed a good linearlity in the range of 1.0 M and the detection limit has been (2.2 M. This method was applicated for the determination of MMI in antithyroid drug without interference of additives.
 Keywords
Antithyroid;2-Mercapto-1-Methyl-imidazole;Differential Pulse Polarography;
 Language
Korean
 Cited by
1.
Analysis of thyrostatic heteroaromatic thioamides (review), Pharmaceutical Chemistry Journal, 2010, 44, 2, 99  crossref(new windwow)
2.
Electrophoretic determination of 1-methyl-2-mercaptoimidazole in the pharmaceutical preparation mercazolyl, Journal of Analytical Chemistry, 2007, 62, 3, 263  crossref(new windwow)
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