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Spectrophotometric Determination of Aminoglycoside Antibiotics Based on their Oxidation by Potassium Permanganate
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 Title & Authors
Spectrophotometric Determination of Aminoglycoside Antibiotics Based on their Oxidation by Potassium Permanganate
El-Didamony, A. M.; Ghoneim, A. K.; Amin, A. S.; Telebany, A. M.;
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 Abstract
A rapid, simple and sensitive validated spectrophotometric methods have been described for the assay of neomycin and streptomycin either in pure form or in pharmaceutical formulations. The proposed methods were based on the oxidation of the studied drugs by a known excess of potassium permanganate in acidic medium and estimating the unreacted permanganate with amaranth dye (method A), acid orange II (method B), indigocarmine (method C), and methylene blue (method D), in the same acid medium at a suitable lmax
 Keywords
Spectrophotometry;Neomycin sulphate;Streptomycin sulphate;Potassium permanganate;Oxidation reactions;Pharmaceutical formulations
 Language
English
 Cited by
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