JOURNAL BROWSE
Search
Advanced SearchSearch Tips
Microwave-Assisted One-Pot Synthesis of Octahydroquinazolinone Derivatives Catalyzed by Thiamine Hydrochloride Under Solvent-free Condition
facebook(new window)  Pirnt(new window) E-mail(new window) Excel Download
 Title & Authors
Microwave-Assisted One-Pot Synthesis of Octahydroquinazolinone Derivatives Catalyzed by Thiamine Hydrochloride Under Solvent-free Condition
Badadhe, Pravin V.; Chate, Asha V.; Hingane, Dattatraya G.; Mahajan, Pravin S.; Chavhan, Namdev M.; Gill, Charansingh H.;
  PDF(new window)
 Abstract
Thiamine hydrochloride (VB1) has been used as an acid catalyst in organic synthesis. One pot three component Biginelli condensation of dimedone, urea/thiourea and substituted aromatic aldehydes catalyzed by 10 mol % of thiamine hydrochloride (VB1) in solvent free condition under microwave irradiation in good to excellent yields has been investigated. Utilization of microwave irradiation, simple reaction conditions, short reaction time, ease of product isolation, and purification makes this manipulation very interesting from an economic and environmental perspective.
 Keywords
Thiamine hydrochloride;Biginelli reaction;Octahydroquinazolinone derivatives;Microwave-irradiation;Solvent-free;
 Language
English
 Cited by
1.
Microwave-Assisted One-Pot Synthesis of Octahydroquinazolinone Derivatives Using Molybdenum Oxide Nanoparticles in Solvent-Free Condition, Journal of Cluster Science, 2014, 25, 5, 1389  crossref(new windwow)
2.
Rapid and mild synthesis of quinazolinones and chromeno[ d ]pyrimidinones using nanocrystalline copper(I) iodide under solvent-free conditions, Chinese Chemical Letters, 2016, 27, 1, 114  crossref(new windwow)
 References
1.
Kidwai, M.; Saxena, S.; Khan, M. K. R.; Thukral, S. S. Eur. J. Med. Chem. 2005, 40, 816. crossref(new window)

2.
Yarim, M.; Sarac, S.; Kilic, K.; ErolS, F. II Farmaco. 2003, 58, 17 crossref(new window)

3.
Yarim, M.; Sarac, S.; Ertan, M.; Kilic, S. F.; Erol, K. Arzneim-Forsch. 2002, 52, 27.

4.
Hassani, Z.; Islami, M. R.; Kalantari, M. Bio. Org. Med. Chem. Lett. 2006, 16, 4479. crossref(new window)

5.
Kantevari, S.; Bantu, R.; Nagarapu, L. Arkivoc. 2006, xvi, 136.

6.
Lin, H.; Zhao, Q.; Xu, B.; Wang, X. J. Mol. Catal. A: Chemical. 2007, 268, 221. crossref(new window)

7.
Hassani, Z.; Islami, M. R.; Kalantari, M. Bioorg. Med. Chem. Letts. 2006, 16, 4479. crossref(new window)

8.
Niralwad, K. S.; Shingate, B. B.; Shingare, M. S. J. Chin. Chem. Soc. 2010, 57, 1.

9.
Tonkikh, N. N.; Strakovs, A.; Petrova, M. V. Chem. Heterocycl. Compds. 2004, 40, 43. crossref(new window)

10.
Loupy, A. Microwaves in organic synthesis, 2nd ed.; Wiley-VCH: Weinheim, 2006.

11.
Varma, R. S. Green Chemistry. 1999, 1, 43. crossref(new window)

12.
Yasuhara, A.; Suzuki, N.; Sakamoto, T. Chem.Pharm. Bull. 2002, 50, 143. crossref(new window)

13.
Amantini, D.; Beleggia, R.; Fringuelli, F.; Pizzo, F.; Vaccaro, L. J. Org. Chem. 2004, 69, 2896. crossref(new window)

14.
Hiyama, T.; Hatanaka, Y. Pure & App. Chem. 1994, 66(7), 1471. crossref(new window)

15.
Sharma, R. K.; Fry, J. L. J. Org. Chem. 1983. 48(12), 2113.

16.
Sun, H.; Di Magno, S. G. J. Am. Chem. Soc. 2005, 127, 2050. crossref(new window)

17.
Mandhane, P. G.; Joshi, R. S.; Nagargoje, D. R.; Gill, C. H. Tetrahedron Lett. 2010, 51, 1490. crossref(new window)

18.
Mandhane, P. G.; Joshi, R. S.; Nagargoje, D. R.; Gill, C. H. Tetrahedron Lett. 2010, 51, 3138. crossref(new window)

19.
Joshi, R. S.; Mandhane, P. G.; Diwakar, S. D.; Gill, C. H. Ultrason. Sonochem. 2009, 17, 298.

20.
Joshi, R. S.; Mandhane, P. G.; Shaikh, M. U.; Kale, R. P.; Gill, C. H. Chin. Chem. Lett. 2010, 21, 429. crossref(new window)

21.
Jadhav, G. R.; Shaikh, M. U.; Kale, R. P.; Gill, C. H. Chin. Chem. Lett. 2009, 20, 292. crossref(new window)

22.
Jadhav, G. R.; Kale, R. P.; Shaikh, M. U.; Gill, C. H. Chin. Chem. Lett. 2009, 20, 535. crossref(new window)

23.
Mandhane, P. G.; Joshi, R. S.; Ghawalkar, A. R.; Jadhav, G. R.; Gill, C. H. Bull. Korean Chem. Soc. 2009, 30(12), 2969. crossref(new window)

24.
Falsone F. S.; Kappe, C. O. Arikivoc. 2001, (II), 122.