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Studies on Some Bioactive 1,1-Bis(2-benzylidene-5-aryliden-1,3-thiadiazolidin-4-one)cyclopropane
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 Title & Authors
Studies on Some Bioactive 1,1-Bis(2-benzylidene-5-aryliden-1,3-thiadiazolidin-4-one)cyclopropane
Panwar, Hemant; Chaudhary, Nidhi; Singh, Sachi; Chawla, Amit;
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 Abstract
Some novel heterocyclic derivatives of 1,1-bis(2-phenyl-5-arylidine-1,3-thiadiazolidin-4-one)cyclopropane 4(a-i) have been synthesized from cyclopropane dicarboxylic acid and substituted thiadiazole moieties. All the synthesized compounds have been characterized by elemental and spectral (I.R., -NMR, Mass) analysis. Furthermore, above said compounds were screened for their antifungal and antibacterial activities. Compound 4c was found the most potent one which further evaluated for lesser toxicity test.
 Keywords
Bis-phenylarylidinylthiadiazolidinone cyclopropane;Antifungal;Antibacterial;Acute toxicity;
 Language
English
 Cited by
1.
Study of Mesoionic Compounds: Synthesis and Pharmacological Evaluation of Several 2-[{(4-Substituted-1-sulphonyl) Sydnon-3-yl}]-1,3,4-thiadiazino(6,5-b)indoles as Antimicrobial, Insecticidal and Antihelmintic Agents, Oriental Journal of Chemistry, 2014, 30, 1, 271  crossref(new windwow)
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