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Synthesis and Biological Studies of Novel Biphenyl-3,5-dihydro-2H-thiazolopyrimidines Derivatives
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 Title & Authors
Synthesis and Biological Studies of Novel Biphenyl-3,5-dihydro-2H-thiazolopyrimidines Derivatives
Maddila, S.; Damu, G.L.V.; Oseghe, E.O.; Abafe, O.A.; Rao, C. Venakata; Lavanya, P.;
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 Abstract
A new series of ethyl 2-(4-substitutedbenzylidene)-5-(3`-(ethoxycarbonyl)biphenyl-4-yl)-7-methyl-3-oxo-3,5-dihydro-2H-thiazolo[3,2-a]pyrimidine-6-carboxylate derivatives () were synthesized. The newly synthesized compounds were characterized by , , , and , , analyses. All newly synthesized compounds were screened for their In vitro antioxidant activity (Scavenging of hydrogen peroxide, Scavenging of nitric oxide radical, and Lipid peroxidation inhibitory activity), antibacterial (Escheria coli, Pseudonmonas aeruginosa (gram-negative bacteria), Bacillus subtillis, Staphylococcus aureus (gram-positive bacteria)) and antifungal (Candida albicans Aspergillus niger) studies.
 Keywords
Biphenyl-3,5-dihydro-2H-thiazolopyrimidines derivatives;Antioxidant activity;Antibacterial;Antifungal activities;
 Language
English
 Cited by
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