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Synthesis and in Vitro Antimicrobial Evaluation of Benzothiazole Incorporated Thiazolidin-4-ones Derivatives
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 Title & Authors
Synthesis and in Vitro Antimicrobial Evaluation of Benzothiazole Incorporated Thiazolidin-4-ones Derivatives
Agarwal, Shikha; Agarwal, Dinesh Kumar; Gautam, Naveen; Agarwal, Kshamta; Gautam, Dinesh Chandra;
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 Abstract
In the course of work on new pharmacologically active antimicrobial agents, we have reported the synthesis of a new class of structurally novel derivatives, incorporating two bioactive structures, a benzothiazole and thiazolidin-4-one, to yield a class of compounds having interesting antimicrobial properties. The antimicrobial properties of the synthesized compounds were investigated against bacteria (Staphylococcus aureus and Escherchia coli) and fungi (Candida albicans and Aspergillus niger) using serial plate dilution method. The structure of the synthesized compounds have been established by elemental analysis and spectroscopic data.
 Keywords
Benzothiazole;Thiazolidin-4-ones;N-(5,7-dimethylbenzo[d]thiazol-2-yl)hydrazine carboxamide;Antimicrobial activity;
 Language
English
 Cited by
1.
Synthesis, antimicrobial, antiquorum-sensing and cytotoxic activities of new series of benzothiazole derivatives, Chinese Chemical Letters, 2015, 26, 12, 1522  crossref(new windwow)
2.
Synthesis and Biological Evaluation of Novel Benzothiazole Derivatives as Potential Anticonvulsant Agents, Molecules, 2016, 21, 3, 164  crossref(new windwow)
3.
Synthesis and Biological Evaluation of Novel Benzothiazole Derivatives as Potential Anticonvulsant Agents, Molecules, 2016, 21, 12, 164  crossref(new windwow)
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