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Hyperpolarization: Sensitivity Boost in Magnetic Resonance Spectroscopy and Imaging
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 Title & Authors
Hyperpolarization: Sensitivity Boost in Magnetic Resonance Spectroscopy and Imaging
Ko, Hyeji; Gong, Gyeonghyeon; Jeong, Gijin; Choi, Ikjang; Seo, Hyeonglim; Lee, Youngbok;
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Hyperpolarization methods are the most emerging techniques in the field of magnetic resonance (MR) researches since they make a contribution to overcoming sensitivity limitation of MR spectroscopy and imaging, leading to new fields of researches, real-time in vivo metabolic/molecular imaging and MR analysis of chemical/biological reactions in non-equilibrium conditions. Make use of enormous signal enrichments, it becomes feasible to investigate various chemical and biochemical systems with low nuclei in real-time. This review deals with the theoretical principals of common hyperpolarization methods and their experimental features. In addition, more detailed theories, mechanisms, and applications of dissolution dynamic nuclear polarization (D-DNP) are discussed.
Hyperpolarization;dissolution DNP;MRS;MRI;real-time measurement;
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