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Distribution of Doublecortin Immunoreactivities in Developing Chick Retina
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  • Journal title : Applied Microscopy
  • Volume 42, Issue 3,  2012, pp.142-146
  • Publisher : Korean Society of Electron Microscopy
  • DOI : 10.9729/AM.2012.42.3.142
 Title & Authors
Distribution of Doublecortin Immunoreactivities in Developing Chick Retina
Kim, Young-Hwa; Sun, Woong;
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 Abstract
Doublecortin (DCX) is a microtuble-associated protein that is required for the migration of immature neuroblasts within the chick and mammalian brain. Although it is generally thought that DCX is expressed only in the neuroblasts, some mature neurons maintain DCX expression; for example, horizontal cells in adult rat retina. In this study, we demonstrate that retinal neural progenitors in the early embryonic stage of the chick also expressed DCX, as do developing ganglion cells and horizontal cells in later stages of development. These findings raise the possibility of a role for DCX in retinal neural progenitors, before they become specialized into neuroblasts in the chick.
 Keywords
Chick embryo;Doublecortin;Retina;Stem cells;
 Language
English
 Cited by
1.
Distinct Features of Doublecortin as a Marker of Neuronal Migration and Its Implications in Cancer Cell Mobility, Frontiers in Molecular Neuroscience, 2017, 10, 1662-5099  crossref(new windwow)
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