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Study on the Physiological Activities of Cleyera japonica Extract
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  • Journal title : Korean Journal of Plant Resources
  • Volume 28, Issue 2,  2015, pp.153-157
  • Publisher : The Plant Resources Society of Korea
  • DOI : 10.7732/kjpr.2015.28.2.153
 Title & Authors
Study on the Physiological Activities of Cleyera japonica Extract
Ahn, JoungJwa; Hwang, Tae-Young; Kim, Hyun-Soo;
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In this study, we investigated the applicability of functional materials by examining a variety of physiological activities with the extract of Cleyera japonica leaf. Cleyera japonica extract showed a low cytotoxicity against murine melanoma B16F10 cells. In little or no cytotoxicity at concentrations, we showed that the treatment with Cleyera japonica extract resulted in a significant increase in the DPPH radical scavenging activity (IC50, 22.90 ㎎/L), similar to ascorbic acid (IC50, 18.65 ㎎/L) and anti-microbial activities against Bacillus subtilis, Escherichia coli, and Candida albicans. In particular, anti-microbial activities against Gram-positive bacteria was high. These results suggest that Cleyera japonica extract could be used as a natural preservative. Additionally, Cleyera japonica extract showed the inhibition of tyrosinase activity (IC50, 178.90 ㎎/L), similar to kojic acid (IC50, 89.13 ㎎/L) and decreased melanin content (IC50, 101.90 ㎎/L) higher than the control arbutin level (IC50, 100.65 ㎎/L), especially. Therefore, these results indicate that Cleyera japonica extract may be an effective material for functional cosmetics such as skin whitening materials.
Cleyera japonica;Antioxidant;Antimicrobial activity;Melanin;Tyrosinase;
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