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Screening of Biological Activity of Solvent Extract from Styela clava Tunic for Fishery Waste Recycling
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 Title & Authors
Screening of Biological Activity of Solvent Extract from Styela clava Tunic for Fishery Waste Recycling
Lee, Sang-Mee; Kang, Eun-Jin; Go, Tae-Hun; Jeong, Seong-Yun; Park, Geun-Tae; Lee, Hee-Sup; Hwang, Dae-Youn; Jung, Young-Jin; Son, Hong-Joo;
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Styela clava tunic is generated in large amounts as a waste from S. clava processing plants and causes environmental problem. Although biological activities of S. clava were reported by many investigators, study on S. clava tunic was little. In this study, therefore, tyrosinase inhibition and antioxidative activities of extracts from S. clava tunic using different solvent were investigated for recycling of the fishery waste. Among extraction methods tested, autoclaved extraction (25.7%) and hot water extraction (18.2%) appeared to be effective for extraction. The highest total phenolic content was 46.6 mg/g in autoclaved extract while the highest flavonoid content was 23.0 mg/g in chloroform extract. All extracts possessed tyrosinase inhibition activity and the inhibition activity was concentration-dependent. Inhibition concentration () against tyrosinase activity was mg/ml in ethanol extract, mg/ml in acetone extract and 0.27 mg/ml in n-butanol extract. Among extracts tested, hot water and autoclaved extracts displayed higher antioxidative activity than organic solvent extracts. Therefore, our data suggest that extract from S. clava tunic may potential candidate for cosmetic product with whitening effect and medicine for diseases caused by various oxidative stresses.
Antioxidant;Solvent extract;Styela clava;Whitening effect;
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수산폐기물인 미더덕껍질 용매 추출물의 항산화 및 항고혈압 활성,이상미;이예람;조광식;박수연;장은영;황대연;정영진;손홍주;

Journal of Environmental Science International, 2015. vol.24. 7, pp.917-925 crossref(new window)
Toxicity of antioxidative extract collected from Styela clava tunics in ICR mice,;;;;;;;;;;

Laboraroty Animal Research, 2015. vol.31. 3, pp.125-133 crossref(new window)
tunics in ICR mice, Laboratory Animal Research, 2015, 31, 3, 125  crossref(new windwow)
Protective effects of the antioxidant extract collected from Styela clava tunics on UV radiation-induced skin aging in hairless mice, International Journal of Molecular Medicine, 2016, 38, 5, 1565  crossref(new windwow)
Ahn, S. H., Jung, S. H., Kang, S. J., Jeong, T. S., Choi, B. D., 2003, Extraction glycosaminoglycans from Styela clava tunic, Kor. J. Biotechnol. Bioeng., 18, 180-185.

Amador, M. L., Jimeno, J., Paz-Ares, L., Cortes-Funes, H., Hidalgo, M., 2003, Progress in the development and acquisition of anticancer agents from marine sources. Ann. Oncol., 14, 1607-1615. crossref(new window)

An, S. H., 2004, Fractionation of glycosaminoglycans extracted from the Styela clava Tunic, MS Dissertation, Gyungsang National University, Jinju.

Azzi, A., Davis, K. J. A., Kelly, F., 2004, Free radical biology-terminology and critical thinking, FEBS Lett., 558, 3-6. crossref(new window)

Blois, M. S., 1958, Antioxidant determinations by the use of a stable free radical, Nature, 181, 1199-1200. crossref(new window)

Cha, Y. J., Lee, H. Y., Jeong, E. J., 2008, Changes of biological activities of two ascidians, Styela calava and Styela plicata by cooking, J. Life Sci., 18, 109-113. crossref(new window)

Cho, Y. J., 2011, Characteristics of cosmetic with whitening compounds from Phellodendron amurense, J. Appl. Biol. Chem., 54, 108-113. crossref(new window)

Dinis, T. C. P., Madeira, V. M. C., Almeida, L. M., 1994, Action of phenolic derivatives (acetaminophen, salicylate, and 5-aminosalicylate) as inhibitors of membrane lipid peroxidation and as peroxyl radical scavengers, Arch. Biochem. Biophys., 315, 161-169. crossref(new window)

Garcia-Fernandez, L. F., Fernando, R., Sanchex-Puelles, J. M., 2002, The marine pharmacy: New antitumoral compounds from the sea. Pharmaceutical News, 9, 495-501.

Jo, Y. G., 1978, The sterol composition of Styela clava, Kor. Fish Soc., 11, 97-101.

Jung, E. S., Park, E., Lee, S. C., 2008, Antioxidant activities of extracts from parts of Styela clava, J. Kor. Soc. Food Sci. Nutr., 37, 1674-1678. crossref(new window)

Jung, S W., Lee, N K., Kim, S J., Han, D. S., 1995, Screening of tyrosinase inhibitor from plants, Kor. J. Food Sci. Technol., 27, 891-896.

Kim, J. J., Kim, S. J., Kim, S. H., Park, H. R., Lee, S. C., 2006, Antioxidant and anticancer activities of extracts from Styela clava according to the processing methods and solvents, J. Kor. Soc. Food Nutr., 35, 278-283. crossref(new window)

Kim, Y. R., Ahn, S. H., Choi, B. D., Kang, S. J., Shin, G. W., Oh, M. J., Jung, T. S., 2004, In vitro examination of chondroitin sulfates extracted Midduck (Styela clava) and Munggae tunics (Halocynthia roretzi) as cosmetic material, J. Kor. Soc. Food Sci. Nutr., 33, 646-652. crossref(new window)

Lee, J. J., Kim, A. R., Seo, Y. N., Lee, M. Y., 2009, Comparison of physicochemical composition of three species of genus Angelica, Kor. J Food Preserv., 16, 94-100.

Lee, K. H, Park, C. S., Hong, B. I., Jung, B. C., Cho, H. S., Jea, Y. G., 1995, Seasonal variations of nutrients in warty sea squirt (Styela clava). J. Kor. Soc. Food Nutr., 24, 268-273.

Lee, S. C., Kim, J. J., Kim, S. J., Kim, S. H., Park, H. R., 2006, Antioxidant and anticancer activities of extracts from Styela clava according to the processing method and solvents, J. Kor. Soc. Food Sci. Nutr., 35, 278-283. crossref(new window)

Lim, N. Y., Kwon, G. J., Kim, Y. S., Baik, S. K., Lim, J. R., Mun, Y. j., Woo W. H., 2004, Inhibitory effect of methanolic extract from Adenophorae radix on melenogenesis, Kor. Ori. Physiol. Pathol. 18, 747-753.

Marcocci, L., Maguire, J. J., Droylefaix, M. T., Packer, L., 1994, The nitric oxide-scavenging properties of Ginkgo biloba extract EGb 761, Biochem. Biophys. Res. Commun., 201, 748-755. crossref(new window)

Marklund, S., Marklund, G., 1974, Involvement of superoxide anion radical in the oxidation of pyrogallol and a convenient assay for superoxide dismutase, Eur. J. Biochem., 47, 469-474. crossref(new window)

Nam, S. H., Choi, H. J., Hwang, S. M., Choi, Y. W., Lee, Y. G., Joo, W. H., 2013, Antimicrobial and anti-oral malodor efficacy of Schizandra chinensis extracts against oral pathogens, J. Life Sci., 23, 443-447. crossref(new window)

Oyaizu, M., 1986, Studies on products of the browning reaction. Antioxidative activities of browning reaction products prepared from glucosamine, Jpn. J. Nutr., 44, 307-315. crossref(new window)

Park, S. M., Lee, B. B., Hwang, Y. M., Lee S. C., 2006, Quality properties of fish paste containing Styela clava, J. Kor. Soc. Food Sci. Nutr., 35, 908-911. crossref(new window)

Prota, G., 1980, Recent advances in the chemistry of melanogenesis in mammals, J. Invest. Dermatol., 75, 122-127. crossref(new window)

Singleton, V. L., Rossi, J. A., 1965, Colorimetry of total phenolics with phosphomolybdic- phosphotungstic acid reagents, Am. J. Enol. Viti., 16, 144-158.

Woo, Y. M., Kim, A. J., Kim, J., Lee, C. H., 2011, Tyrosinase inhibitory compounds isolated from Persicaria tinctoria flower, J. Appl. Biol. Chem., 54, 47-50. crossref(new window)

Yagi, A., Kanbara, T., Morinobu, N., 1987, Inhibition of mushroom-tyrosinase by Aloe extract, Planta Med., 53, 515-517. crossref(new window)

Zhishen, J., Mengcheng, T., Jianming, W., 1999, The determination of flavonoid contents in mulberry and their scavenging effects on superoxide radicals, Food Chem., 64, 555-559. crossref(new window)