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Immunostimulation Effects of Mice Fed with Cell Lysate of Lactobacillus plantarum Isolated from Kimchi
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  • Journal title : KSBB Journal
  • Volume 13, Issue 4,  1998, pp.424-430
  • Publisher : Korean Society for Biotechnology and Bioengineering
  • DOI :
 Title & Authors
Immunostimulation Effects of Mice Fed with Cell Lysate of Lactobacillus plantarum Isolated from Kimchi
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 Abstract
Immunositmulation effects of the mice fed with the cell lysate of Lactobacillus plantarum isolated from Kimchi were studied. The mice group fed with cell lysate was different from the control group on the degree of immune responses, e.g. 1) proliferation of splenocytes and Peyer's patch cells, 2) production of nitric oxide (NO) by peritoneal macrophages, 3) production of intestinal secretory lgA (slgA), 4) variation of TNF- and IL-2 concentration in blood, 5) production of specific lgG against sheep red blood cells. A general enhancement in enteric and systemic immune responses was observed with a simple oral administration of immunostimulators. With the oral feeding of L. plantarum, not only the total amount of gut secretion antibody, but also the binding capacity of antibodies to the enteric microorganisms including L. plantarum was increased. These experimental results clearly showed that the oral feeding of immunostimulators gave multifunctional effects on the mucosal and systemic immune systems of mice.
 Keywords
Lactobacillus plantarum;Kimchi;immunostimulation effect;oral administration;
 Language
Korean
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