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Characterization of an Indigenous Antimicrobial Substance-producing Paenibacillus sp. BCNU 5011
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  • Journal title : KSBB Journal
  • Volume 26, Issue 2,  2011, pp.100-106
  • Publisher : Korean Society for Biotechnology and Bioengineering
  • DOI : 10.7841/ksbbj.2011.26.2.100
 Title & Authors
Characterization of an Indigenous Antimicrobial Substance-producing Paenibacillus sp. BCNU 5011
Choi, Hye-Jung; Kim, Ya-Ell; Bang, Ji-Hun; Kim, Dong-Wan; Ahn, Cheol-Soo; Jeong, Young-Kee; Joo, Woo-Hong;
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 Abstract
Strain BCNU 5011 was isolated from forest soil samples collected in the Taebaek mountain in the Gangwon province, Korea. The biochemical, physiological and 16S rRNA sequence analysis strongly indicated that this isolate was most closely related to Paenibacillus polymyxa. A maximum production level of antimicrobial substances of Paenibacillus sp. BCNU 5011 was achieved under aerobic incubation at for 3 days in SST broth.Paenibacillus sp. BCNU 5011 showed a broad spectrum of activity against Gram positive and Gram negative bacteria, including methicllinresistant Staphylococcus aureus (MRSA). Paenibacillus sp. BCNU 5011 was also shown to inhibit the growth of different potential human pathogenic bacteria and fungi in vitro. Peptide extract showed better antimicrobial activity than solvent extracts. But active antimicrobial compounds might be included in both peptide extract and solvent extracts. Further separation, purification and identification of active principles leads project to develop antimicrobial agents and anti-MRSA agents.
 Keywords
Paenibacillus polymyxa;Antimicrobial activity;Human pathogenic fungi;Methicllin-Resistant Staphylococcus aureus;
 Language
Korean
 Cited by
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천일염과 녹차를 발효시켰을 때 Catechin류의 추출량 변화,윤현;오혜종;최성우;

한국콘텐츠학회논문지, 2012. vol.12. 11, pp.278-285 crossref(new window)
1.
The Antibacterial Activity Against Fish Pathogen of Paenibacillus sp. MK-11 Isolated from Jeju Coast, Journal of Life Science, 2014, 24, 8, 880  crossref(new windwow)
2.
Difference of Catechins Extracted Level when Fermented Sun-dried Salt and Green Tea, The Journal of the Korea Contents Association, 2012, 12, 11, 278  crossref(new windwow)
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