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Effects of Ethanol Extract of the Rhodiola Sachalinensis for Anti-oxidation and Blood Pressure and Skeletal Muscles Contractility in Rat
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  • Journal title : KSBB Journal
  • Volume 26, Issue 3,  2011, pp.211-216
  • Publisher : Korean Society for Biotechnology and Bioengineering
  • DOI : 10.7841/ksbbj.2011.26.3.211
 Title & Authors
Effects of Ethanol Extract of the Rhodiola Sachalinensis for Anti-oxidation and Blood Pressure and Skeletal Muscles Contractility in Rat
Jin, Yinzhe; Cheng, Yu-dong; Lee, Kwang-Jin; Jung, Yong-An; Row, Kyung-Ho;
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 Abstract
To study the effects of ethanol extract of the Rhodiola Sachalinensis on the anti-oxidation and blood pressure and skeletal muscles contractility in rats. The ethanol extracts and fractions of Rhodiola Sachalinensis were determinated the anti-oxidation effects by DPPH(1,1-dipenyl-2-picrylhydrazyl) method and comparing with the BHA (Butylated hydroxyanisole) and AA(Ascorbic acid). The gastrocnemius and soleus muscle contractility were observed by stimulating the sciatic nerve with electricity after affusing stomach with ethanol extract of the 200 mg/kg dosage of Rhodiola Sachalinensis for 4 weeks. The ethanol extract of the Rhodiola Sachalinensis could shorten latent period, increase maximal contractive extent and time and relaxative time at the twitch and complete tetanus of gastrocnemius and soleus muscles. The ethanol extract of the Rhodiola Sachalinensis shows high anti-oxidation effect and can enhance skeletal muscles contractility in rats.
 Keywords
Rhodiola Sachalinensis;Anti-oxidation;Blood Pressure;Skeletal Muscles Contractility;
 Language
Korean
 Cited by
1.
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생약학회지, 2012. vol.43. 3, pp.250-256
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