Advanced SearchSearch Tips
Anticariogenic Activities of Lactobacillus sakei K-7 Isolated from Kimchi
facebook(new window)  Pirnt(new window) E-mail(new window) Excel Download
  • Journal title : KSBB Journal
  • Volume 26, Issue 6,  2011, pp.513-516
  • Publisher : Korean Society for Biotechnology and Bioengineering
  • DOI : 10.7841/ksbbj.2011.26.6.513
 Title & Authors
Anticariogenic Activities of Lactobacillus sakei K-7 Isolated from Kimchi
Moon, Jin-Seok; Ahn, Ji-Eun; Han, A-Reum; Heo, Jeong-Seon; Eom, Hyun-Ju; Shin, Chul-Soo; Choi, Hye-Sun; Han, Nam-Soo;
  PDF(new window)
The occurrence of dental caries is mainly associated with oral pathogens, especially cariogenic Streptococcus mutans. The aim of this study was to isolate and characterize lactic acid bacterium showing inhibitory activity against cariogenic Streptococcus mutans. As results, an isolate with strong inhibitory activity was obtained from Kimchi and it was identified as Lactobacillus sakei by API and 16S rRNA gene analyses. This strain secreted an inhibitory compound in cell growth medium and the activity of the compound was completely disappeared by proteinase K revealing the fact that the compound is proteinous substance, bacteriocin. Optimal culture condition for bacteriocin production by Lb. sakei K-7 was at pH 7.5 and for 18 h. Oral administration of this isolate may give anticariogenic and probiotic effects on hosts.
Dental caries;Kimchi;Lactobacillus sakei;Bacteriocin;
 Cited by
동치미로부터 분리한 Lactobacillus sakei J4의 항균활성 및 생균제로서 특성,박중현;오덕환;정하열;

산업식품공학, 2012. vol.16. 2, pp.122-128
Hamada, S., T. Ooshima, M. Torii, H. Imanishi, N. Masuda, S. Sobue, and S. Kotani (1978) Induction in experimental animals by clinical strains of Streptococcus mutans isolated from japanese. Children Microbiol. Immunol. 22: 301-314. crossref(new window)

Mosci, F., S. Perito, S. Bass, and A. Capuano (1990) The role of Streptococcus mutans in human caries. Minerva Stomatol. 39: 413-429.

Gibbson, R. J. and J. Van Houte (1973) On the formation dental plaque. J. Periodontol. 44: 347-360. crossref(new window)

Jang, G. H., B. Y. Ahn, S. H. Oh, D. S. Choi, and Y. J. Kwon. (2000) Anticariogenic effects of coptis chinensis franch extract. Korean J. Food Sci. Technol. 32: 1396-1402.

You, Y. S., K. M. Park, and Y. B. Kim (1993) Antimicrobial activity of some medical herbs and spices against Streptococcus mutans. Korean J. Appl. Microbial Biotechnol. 21: 187-191.

Cho, Y. J. (2000) Isolation of 3-galloylprocyanidin B3, a glucosyltransferase inhibition from the Korean green tea leaves. Agri. Chem. Biotechnol. 43: 273-276.

Nakahara, K., S. Kawabata, H. Ono, K. Ogura, T. Tanaka, T. Ooshima, and S. Hamada (1993) Inhibitory effect of oolong tea polyphenols on glycosyltransferases of mutans streptococci. Appl. Environmental Microbiol. 4: 968-964.

Ooshima, T., A. Izumitani, T. Minami, S. Yoshida, and S. Hamada (1992) Non cariogenicity of maltitol in specific pathogen-free rats infected with mutans streptococci. Caries Res. 26: 33-37. crossref(new window)

Lee, M. K., K. K. Rhee, J. K. Kim, S. M. Kim, J. W. Jeong, and D. J. Jang (2007) A survey of research papers on korean kimchi and R&D trends. Kor. J. Food Culture 22: 104-114.

Aly, S., A. T. Cheik, H. N. Imael, and S. Alfred (2004) Antibacterial activities of lactic acid bacteria strain isolated from burkina faso fermentated milk. Pak. J. Nutri. 3: 174-179. crossref(new window)

Beak, S. S. and C. Ahn (1997) Antibiosis and bacteriocin production of lactic acid bacteria isolated from Kimchi. J. Food Sci. Nutr. 2: 109-120.

Kim, D. S. (2002) Characteristics of the bacteriocin from Lactobacillus sp. Oh-B3. Kor. J. Microbiol. Biotechnol. 30: 184-188.

Tagg, J. R. and A. R. McGiven (1971) Assay systems for bacteriocins. Appl. Microbiol. 21: 943.

Holt, J. G., N. R. Krieg, P. H. A. Sneath, J. T. Staley, and S. T. Williams (1994) Regular, Nonsporing Gram-positive Rods, pp. 565-570. In: Bergey's Manual of Determinative Bacteriology. 9thed. Williams and Wilkins. Baltimore, USA.

Felske, A. and A. D. L. Akkermans (1998) Spatial homogeneity of abundant bacterial 16S rRNA molecules in grassland soils. Microb. Ecol. 36: 31-36. crossref(new window)

Aasen, I. M., T. Moretro, T. Katla, L. Axelsson, and L. Storro (2000) Influence of complex nutrients, temperature and pH bacteriocin production by Lactobacillus sakei CCUF 42678. Appl. Microbiol. Biotechnol. 53.

Parente, E. and A. Ricciardi (1994) Influence of PH on the production of enterocin 1146 during batch fermentation. Lett. Appl. Microbiol. 1912-1915.