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Optimization of Reduction of 3-chloro-4-fluoropropiophenone by Whole Cells of Saccharomyces cerevisiae
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  • Journal title : KSBB Journal
  • Volume 26, Issue 6,  2011, pp.569-571
  • Publisher : Korean Society for Biotechnology and Bioengineering
  • DOI : 10.7841/ksbbj.2011.26.6.569
 Title & Authors
Optimization of Reduction of 3-chloro-4-fluoropropiophenone by Whole Cells of Saccharomyces cerevisiae
Lee, Hae-Ryong; Jeong, Min; Yoo, Ik-Keun; Hong, Soon-Ho;
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Reduction of 3-chloro-4-fluoropropiophenone by Saccharomyces cerevisiae as a whole cell biocatalyst was optimized. Effects of glucose, S. cerevisiae and 3-chloro-4-fluoropropiophenone concentrations on conversion of reduction reaction was investigated. Optimum concentrations of glucose, S. cerevisiae and 3-chloro-4-fluoropropiophenone were 100, 40 and 20 g/L, respectively. At optimum condition, 100% of conversion was achieved in 12 hours of reaction.
3-Chloro-4-fluoropropiophenone;Saccharomyces cerevisiae;Reduction;Biotransformation;
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