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Dietary Effects of Polymannuronate Added to Hamburger Buns on Lipid Metabolism in Rats
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 Title & Authors
Dietary Effects of Polymannuronate Added to Hamburger Buns on Lipid Metabolism in Rats
Joh, Ihn-Seon; Kim, In-Hye; Kwon, Mi-Jin; Nam, Taek-Jeong;
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The dietary fiber alginic acid has no nutritional value; however, it decreases the utilization of nutrients by the body and can prevent obesity, hyperlipidemia, arteriosclerosis, constipation, and colon cancer. The low-molecular-weight alginic acid polymannuronate improves serum and liver lipid metabolism by decreasing cholesterol levels in high-cholesterol groups and may be used to control high blood pressure. Previously, we showed that polymannuronate, a physiologically active agent from seaweed, has a lipid-lowering effect and preventative role in colon cancer. In addition, the differentiation of polymannuronate-treated adipocytes was inhibited, triggering decreased leptin expression. This study examined ways to increase dietary satisfaction with and improve the nutritional quality of polymannuronate using hamburger buns supplemented with polymannuronate. Twenty male Sprague-Dawley rats were divided into two groups: the control group was fed hamburger buns containing 6% gluten, while the experimental group was fed hamburger buns containing 6% gluten and 10% polymannuronate. The serum triglyceride, phospholipid, and total and free cholesterol levels of the rats in the experimental group were decreased compared with those of the controls. The serum aspartate aminotransferase activity levels did not differ between the two groups. This study demonstrates that polymannuronate has beneficial effects on lipid metabolism and may be commercially useful.
Hamburger buns;Polymannuronate;Lipid metabolism;Nutritional quality;
 Cited by
저분자 알긴산의 효소적 생산과 지방세포 분화 억제 효과,박미지;김연희;김군도;남수완;

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