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Dual-Chamber Technology: Safe and Convenient Drug Delivery for Lyophilized Biologics
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 Title & Authors
Dual-Chamber Technology: Safe and Convenient Drug Delivery for Lyophilized Biologics
Moore, John;
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 Abstract
Biologics present a challenge to both the manufacturer and end user. They must usually be formulated as parenterals. However, they are often unstable in liquid form, due to their complex structure and composition. In that case, they must be manufactured using highly specialized processes, such as lyophilization (freeze-drying). Lyophilization nearly eliminates stability issues. Reducing a compound`s sensitivity to temperature prolongs its shelf life. However, reconstitution can be cumbersome, involving multiple steps that increase the potential for error. Dual-chamber technology provides an effective alternative, combining a lyophilized drug and diluent in a closed system and enabling reconstitution in a few simple steps.
 Keywords
Dual-chamber;Lyophilization;Injectable device;
 Language
English
 Cited by