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Anti-allergic effect of Lactobacillus rhamnosus IDCC 3201 isolated from breast milk-fed Korean infant
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 Title & Authors
Anti-allergic effect of Lactobacillus rhamnosus IDCC 3201 isolated from breast milk-fed Korean infant
Lee, Seung-Hun; Kang, Jae-Hoon; Kang, Dae-Jung;
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 Abstract
We investigated 23 lactic acid bacteria isolated from Korean breast milk-fed infant in order to select strains which show superior anti-allergic effect. The candidates were cultivated and then we obtained dried powders of tyndallized cells and supernatant concentrate separately. Screening was carried out with down-regulation of interleukin (IL) 4 and up-regulation of IFN- in mouse splenocytes. As a result of the screening, we selected Lactobacillus rhamnosus IDCC 3201 (RH3201) for oral feeding to ovalbumin-sensitized BALB/c mice. Oral administration of RH3201 as dead cell bodies and supernatant concentrate suppressed hyper-production of serum immunoglobulin (Ig) E levels compared to vehicle group. Such anti-allergic effects were achieved by improvement of the balance between cytokines produced from type-1 helper T (Th1) and type-2 helper T (Th2) lymphocytes. Therefore, RH3201 has potential to improve atopic symptoms by immunomodulatory effect.
 Keywords
Lactobacillus rhamnosus IDCC 3201;immunomodulation;tyndallization;immunoglobulin E;
 Language
Korean
 Cited by
1.
Therapeutic effect of tyndallizedLactobacillus rhamnosusIDCC 3201 on atopic dermatitis mediated by down-regulation of immunoglobulin E in NC/Nga mice, Microbiology and Immunology, 2016, 60, 7, 468  crossref(new windwow)
 References
1.
Borish, L. 1998. Updates on cell and cytokine. J. Allergy Clin. Immun. 101, 293-297. crossref(new window)

2.
Chauviere, G., Coconnier, M.H., Kerneis, S., Arlette, D.M., Joly, B., and Alain, L.S. 1992. Competitive exclusion of diarrheagenic Escherichia coli (ETEC) from human enterocyte-like Caco-2 cells by heat-killed Lactobacillus. FEMS Microbiol. Lett. 91, 213-217. crossref(new window)

3.
Claes, I., Segers, M., Verhoeven, T., Dusselier, M., Sels, B., Keersmaecker, S., Vanderleyden, J., and Lebeer, S. 2012. Lipoteichoic acid is an important microbe-associated molecular pattern of Lactobacillus rhamnosus GG. Microb. Cell Fact. 11, 161.

4.
Cross, M.L., Stevenson, L.M., and Gill, H.S. 2001. Anti-allergy properties of fermented foods : an important immunoregulatory mechanism of lactic acid bacteria. Int. Immunopharmacol. 1, 891-901. crossref(new window)

5.
Fujiwara, D., Inoue, S., Wakabayashi, H., and Fujii, T. 2004. The anti-allergic effects of lactic acid bacteria are strain dependent and mediated by effects on both Th1/Th2 cytokine expression and balance. Int. Arch. Allergy Immunol. 135, 205-215. crossref(new window)

6.
Gail, C.M. 2007. Use of probiotics: Benefits of a balanced microbiome in the intestinal tract. National Parent Club Canine Health Conference pp. 19-21.

7.
Herich, R. and Levkut, M. 2002. Lactic acid bacteria, probiotics and immune system. Vet. Med. Czech. 47, 169-180.

8.
Ishida, Y., Nakamura, F., Kanzato, H., Sawada, D., Hirata, H., Nishimura, A., Kajimoto, O., and Fujiwara, S. 2005. Clinical effects of Lactobacillus acidophilus strain L-92 on perennial allergic rhinitis : A double-blind, placebo-controlled study. J. Dairy Sci. 88, 527-533. crossref(new window)

9.
Kato, I., Tanaka, K., and Yokokura, T. 1999. Lactic acid bacterium potently induces the production of interleukin-12 and interferon-$\gamma$ by mouse splenocytes. Int. J. Immunopharmacol. 21, 121-131. crossref(new window)

10.
Kelly, D., Conway, S., Aminov, R. 2005. Commensal gut bacteria: mechanisms of immune modulation. Trends Immunol. 26, 326-333. crossref(new window)

11.
Majamaa, H. and Isolauri, E. 1997. Probiotics : A novel approach in the management of food allergy. J. Allergy Clin. Immunol. 99, 179-185. crossref(new window)

12.
Retnaninggtyas, L.P., Sudarmo, S.M., Harsono, A., and Damanik, S.M. 2008. Effect of probiotic on the fecal sIgA level in preterm infants. Paediatr. Indones 48, 246-252.

13.
Schwandner, R., Dziarski, R., Wesche, H., Rothe, M., and Kirsehning, C.J. 1999. Peptidoglycan and lipoteichoic acid-induced cell activation is mediated by toll-like receptor 2. J. Biol. Chem. 274, 1746-1749.

14.
Styriak, I., Nemcova, R., Chang, Y.H., and Ljungh, A. 2003. Binding of extracellular matrix molecules by probiotic bacteria. Lett. Appl. Microbiol. 37, 329-333. crossref(new window)

15.
Vercelli, D. 1995. Immunoglobulin E regulation in humans, 1989-1994. Allergy, 50, 5-8.

16.
Xu, M., Zhao, M., Yang, R., Zhang, Z., Li, Y., and Wang, J. 2013. Effect of dietary nucleotides on immune function in Balb/C mice. Int. Immunopharmacol. 17, 50-56. crossref(new window)

17.
Yazdanbakhsh, M., Kremsner, P.G., and van Ree, R. 2002. Allergy, parasites, and the hygiene hypothesis. Science 296, 490-494. crossref(new window)

18.
Yu, J.H., Jang, S.O., Kim, B.J., Song, Y.H., Kwon, J.W., Kang, M.J., Choi, W.A., Jung, H.D., and Hong, S.J. 2010. The effects of Lactobacillus rhamnosus on the prevention of asthma in a murine model. Allergy Asthma Immunol. Res. 2, 199-205. crossref(new window)