JOURNAL BROWSE
Search
Advanced SearchSearch Tips
Cytotoxicity and Antioxidative Activity of Artemisiae Argi Folium Alcoholic Extracts and Their Fractions
facebook(new window)  Pirnt(new window) E-mail(new window) Excel Download
 Title & Authors
Cytotoxicity and Antioxidative Activity of Artemisiae Argi Folium Alcoholic Extracts and Their Fractions
Lee, Kyoung-In; Cho, Joo-Hyun; Pyo, Byoung-Sik;
  PDF(new window)
 Abstract
This experiment was carried out to obtain the cytotoxicity and antioxidative activity of Artemisiae Argi Folium. The total polyphenol contents in the ethyl acetate fraction of the ethanol extract and the methanol extract were 430.27mg/g and 427.84mg/g, respectively. In DPPH radical scavenging ability, values of the ethyl acetate fraction of the ethanol extract and the methanol extract were 32.64 and 27.70 as the same level of statistical with ascorbic acid. In the cytotoxicity measurement by MTT assay, the chloroform and hexane fraction, and each extract were exhibited higher cytotoxicity than the other fractions. In particular, the ethyl acetate fractions appeared high activity in DPPH radical scavenging ability were began to show cytotoxicity in 125 . As a result, the ethyl acetate fraction of Artemisiae Argi Folium extract was the most highly active fraction in antioxidative activity. However, for the use of extracts and fractions from Artemisiae Argi Folium to related fields, the setting of appropriate concentration is required.
 Keywords
Artemisiae Argi Folium;Cytotoxicity;Antioxidative Activity;
 Language
Korean
 Cited by
1.
애엽(艾葉)의 미토콘드리아 보호 효과,최희윤;제갈경환;김영우;이정우;조수아;조일제;김상찬;

대한한의학방제학회지, 2013. vol.21. 2, pp.63-71 crossref(new window)
1.
Cytoprotective Effects of Artemisia princeps Extract through Inhibition of Mitochondrial Dysfunction, Herbal Formula Science, 2013, 21, 2, 63  crossref(new windwow)
 References
1.
Blois MS. (1958). Antioxidant determinations by the use of a stable free radical. Nature. 181:1199-1200. crossref(new window)

2.
Branen AL. (1975). Toxicological and biochemistry of butylated hydroxyanisole and butylated hydroxytoluene. Journal of the American Oil Chemists' Society. 52:59-65. crossref(new window)

3.
Choi SR, You DH, Kim JY, Park CB, Ryu J, Kim DH and Eun JS. (2008). Antioxidant and antimicrobial activities of Artemisia capillaris Thunberg. Korean Journal of Medicinal Crop Science. 16:112-117.

4.
Choi SR, You DH, Kim JY, Park CB, Kim DH and Ryu J. (2009). Antioxidant activity of methanol extracts from Cudrania tricuspidata Bureau according to harvesting parts and time. Korean Journal of Medicinal Crop Science. 17:115-120.

5.
Eom HJ, Kim SM, Pyo BS and Lee KI. (2009). Changes of physiological activity by drying temperature in leaf of Eriobotrya japonica. Korean Journal of Pharmacognosy. 40:178-183.

6.
Farag RS, Badei AZMA and Baroty GSA. (1989). Influence of thyme and clove essential oils in cotton seed oil oxidation. Journal of the American Oil Chemists' Society. 66:800-806. crossref(new window)

7.
Fridovich I. (1989). Superoxide dismutase an adaption to paramagnetic gas. Journal of Biological Chemistry. 264:7761-7762.

8.
Im DY and Lee KI. (2011). Antioxidative, antibacterial activity and tyrosinase inhibitory activity of the extract and fractions from Taraxacum coreanum Nakai. Korean Journal of Medicinal Crop Science. 19:238-245. crossref(new window)

9.
Kim HT, Kim JW, Lim MK, Jin TW, Yeo SG, Jang KH, Oh TH and Lee KW. (2007). Cytotoxicity effect of Artemisia capillaris extracts on the cancer cells on in vitro. Journal of Veterinary Clinics. 24:367-371.

10.
Lee HH and Lee SY. (2008). Cytotoxic and antioxidant effects of Taraxacum coreanum Nakai. and T. officinale WEB. extracts. Korean Journal of Medicinal Crop Science. 16:79-85.

11.
Lee KI, Yang SA, Pyo BS and Kim SM. (2011). Antibacterial activity against pathogens of acne and tyrosinase inhibitory activity of extract and fractions from bark of Prunus sargentii. Korean Journal of Pharmacognosy. 42:155-160.

12.
Lee MK, Choi GP, Ryu LH, Lee GY, Yu CY and Lee HY. (2004). Enhanced immune activity and cytotoxicity of Artemisia capillaris Thunb. extracts against human cell lines. Korean Journal of Medicinal Crop Science. 12:36-42.

13.
Lee SM, Kim MG, Lee SY and Kang TH. (2010). Effects of Artemisia pronceps extract on bone metabolism. Journal of the Korean Society of Food Science and Nutrition. 39:363-368. crossref(new window)

14.
Liu RH. (2004). Potential synergy of phytochemicals in cancer prevention : mechanism of action. The Journal of Nutrition. 134:3479S-3485S.

15.
Manach C, Williamson G, Morand C, Scalbert A and Remesy C. (2005). Bioavailability and bioefficacy of polyphenols in humans. The American Journal of Clinical Nutrition. 81:230S-242S.

16.
Miller Y, Jouglard J, Steinmetz MD, Tognetii P, Joanny D and Arditti J. (1981). Toxicity of some essential plant oils. Clinical Toxicology. 8:1485-1487.

17.
Moreno MIN, Isla MIN, Sampietro AR and Vattuone MA. (2000). Comparison of the free radical-scavenging activity of propolis from several region of Argentina. Journal of Ethnopharmacology. 71:109-114. crossref(new window)

18.
Oh YJ, Seo HR, Choi YM and Jung DS. (2010). Evaluation of antioxidant activity of the extracts from the aerial parts of Cnidium officinale Makino. Korean Journal of Medicinal Crop Science. 18:373-378.

19.
Park WS. (2008). Study on biological effect of water extract from Artemisia argi folium on mouse macropharge Raw 264.7 cells. Korean Journal of Oriental Physiology and Pathology. 22:815-820.

20.
Park WS. (2009). Effect of water extract from Artemisia argi folium on mouse macropharge stimulated by LPS. Korean Journal of Herbology. 24:151-157.

21.
Qureshi S, Ageel AM, al-Yahya MA, Tarig M, Mossa TS and Shah AH. (1990). Preliminary toxicity studies on ethanol extracts of the aerial parts of Artemisia abyssinica and A. inculta in mice. Journal of Ethnopharmacology. 28:157-162. crossref(new window)

22.
Ryu MJ, Lee SY, Park Y and Yang YK. (2010). Antioxidative activities and antifungal effect against Malassezia furfur in the extracts from 6 spp. medicinal plants. Journal of Korean Society of Cosmetology. 16:120-128.

23.
Shin KM, Park YM, Kim IT, Hong SP, Hong JP and Lee KT. (2003). In vitro antiinflammatory activity of amygdalin in murine macrophage Raw264.7 cells. Korean Journal of Pharmacognosy. 34:223-227.

24.
Videla LA and Fermandez V. (1988). Biochemical aspects of cellular oxidative stress. Archivos de biologia y medicina experimentales. 21:85-92.

25.
Yoon WJ, Lee JA, Kim KN, Kim JY and Park SY. (2007). In vitro anti-inflammatory activity of the Artemisia fukudo extracts in murine macrophage RAW 264.7 cells. Korean Journal of Food Science and Technology. 39:464-469.