Advanced SearchSearch Tips
Effect of Solubility of Thiamine Dilauryl Sulfate Solution through the Manufacture of the Nano Paticles on Antifungal Activity
facebook(new window)  Pirnt(new window) E-mail(new window) Excel Download
 Title & Authors
Effect of Solubility of Thiamine Dilauryl Sulfate Solution through the Manufacture of the Nano Paticles on Antifungal Activity
Seo, Yong-Chang; Choi, Woon-Yong; Lee, Choon-Geun; Cho, Jeong-Sub; Yim, Tae-Bin; Jeong, Myoung-Hoon; Kim, Sung-Il; Yoon, Won-Byung; Lee, Hyeon-Yong;
  PDF(new window)
Conventional Thiamine Dilauryl Sulfate (TDS) powder has a low stability. In order to solve this problem, this study was performed to improve the solubility of TDS. The process for enhance solubility of TDS was nano grinding mill and ultrasonic dispersion process. TDS paticle was manufactured to nano size through nano grinding mill process. The size of TDS nanoparticle was measured as average 220 nm by DLS. And The TDS nanoparticle in water solution manufactured through ultrasonic dispersion process. The TDS nanoparticle in water solution was showed the highest solubility with 40% ethanol. These results was increased the concentration of TDS from 200 ppm to 240 ppm in water solution. The TDS nanoparticle in water solution showed diameter of Colletotrichum gloeosporioides growth with smaller than about 1.56 cm compared to the TDS paticle in water solution at same concentration. Also, TDS nanoparticle in water solution showed growth inhibition activity as 59.2% with higher than about 10% compared to the TDS paticle water solution in same concentration. Finally, TDS nanoparticle in water solution was increased solubility through nano grinding mill and ultrasonic dispersion process. Also, the increase of concentration in TDS nanopaticle in water solution according to solubility enhancement lead to an result enhancement of antifungal activity. Consequently, we suggested that the TDS nanoparticle in water solution was more effective than TDS particle in water solution owing to the sub-cellular particle size, ability to persistence and targeting to cell membrane of Colletotrichum gloeosporioides. Furthermore we expected the applicating possibility with bio pesticide.
Thiamine Dilauryl Sulfate;Nanopaticle Solution;Solubility;Antifungal Activity;Biopesticide;
 Cited by
Effect of Nanoencapsulated Vitamin B1 Derivative on Inhibition of Both Mycelial Growth and Spore Germination of Fusarium oxysporum f. sp. raphani, International Journal of Molecular Sciences, 2013, 14, 2, 4283  crossref(new windwow)
An SM, Lee DS, Kim MS, Choi CS, Lee JB, Jang HS and Son HY. (2009). Bioactivity of the extract of Coptis chinensis: Invitro antifungal activity against Phytophthora capsici and growth-promotion effect in red-pepper. Korean Journal of Microbiology and Biotechnology. 37:280-286.

Jo EK. (1984). Plant pathogens and pest control pesticides. The Bimonthly Magazine for Agrochemicals and Plant Protection. 5:33-41.

Kim CS, Lee JP, Song JH, Lim EK, Chung SJ, Ha SY and Moon BJ. (2001). Development of biofungicide for control of gray mold rot of eggplant caused by Bortrytis cinerea and bioassay in the greenhouse condition. Korean Journal of Life Science. 11:235-341.

Kim HS, Cho YH and Lee DK. (2005). A study on antimicrobial activity and preservative effect of thiamine dilauryl sulfate in cosmetics. The Korean Oil Chemists' Society. 22:212-218.

Kim MH, Ko HS, Yook YM and Kim HS. (2008). Isolation and characterization of microorganisms with broad antifungal activity against phytopathogenic fungi. Korean Journal of Biotechnology and Bioengineering. 23:219-225.

Kim SH, Baek JH, Song YR, Sin MJ and Lee IS. (2009). Characterization and phytotoxicity of Zn, Zn oxide nanoparticles. Journal of Korean Society of Environmental Engineers. 31:1129-1134.

Ko SW, So IS and Huh MR. (2009). Study on antifungal activity of Aloe arborescens M. for a potential bio-pesticide. Journal of Agriculture and Life Science. 43:35-44.

Lee MJ, Ha JH and Ha SD. (2010). Synergistic effect of vitamin $B_{1}$ on sanitizer and disinfectant treatments for reduction of Bacillus cereus in rice. Journal of Food Safety. 30:1-11. crossref(new window)

Lee YH. (2002). Use of vitamin B1 as agents for controlling plant diseases. Korea Patent. 7,011,615.

Park CM, Bae JY, Joung MS and Choi JW. (2011). Whitening effect of 3-O-ctyl-L-acorbic aid. Journal of the Society of Cosmetic Scientists of Korea. 37:91-96.

Saxena A, Sachin K, Bohidar HB and Verma AK. (2005). Effect of molecular weight heterogeneity on drug encapsulation effciency of gelatin nano-particles, Colloids and Surfaces B: Biointerfaces. 45:42-48. crossref(new window)

Seo SY and Kim YG. (2010). Study on development of novel biopesticides using entomopathogenic bacterial culture broth of xenorhabdus and photorhabdus. Korean Society of Applied Entomology. 49:241-249. crossref(new window)

Seo YC, Cho JS, Jeong HY, Yim TB, Cho KS, Lee TW, Jeong MH, Lee GH, Kin SI, Yoon WB and Lee HY. (2011). Enhancement of antifungal activity of anthracnose in pepper by nanopaticles of thiamine dilauryl sulfate. Korean Journal of Medicinal Crop Science. 19:198-240. crossref(new window)