JOURNAL BROWSE
Search
Advanced SearchSearch Tips
Antioxidant Activity and Whitening Effect of Forsythiae Fructus Extracts
facebook(new window)  Pirnt(new window) E-mail(new window) Excel Download
 Title & Authors
Antioxidant Activity and Whitening Effect of Forsythiae Fructus Extracts
Yang, Seo-Jin; Choe, Tae-Boo;
  PDF(new window)
 Abstract
The Forsythiae Fructus is an oriental medicine containing various lignans. In this study, the Forsythiae Fructus were extracted by hot water (Sample 1), hot water after bio-conversion using Lactobacillus strain (Sample 2-LP2, 2-LA, 2-LC, 2-LL, 2-BL and 2-LM) and 70% ethanol (Sample 3). Total polyphenol and flavonoid contents were improved by bio-conversion process using Lactobacillus strain, compared to water extract. Especially, sample 2-LL and 2-LA which had shown the high total polyphenol and flavonoid content in antioxidant activity. Also, sample 2-LL and 2-LA showed higher melanin generation inhibitory activity as of 55%, 53% in maximum extract concentration of . In the anti-inflammation test of the Forsythiae Fructus extracts, nitric oxide (NO) synthesis was inhibited. Specially, both 70% Forsythiae Fructus ethanol extract and sample 2-BL which have shown the relatively higher 1,1-diphenyl-2-picryl-hydrazyl (DPPH) radical scavenging and superoxide dismutase (SOD) like activities. In conclusion, the Forsythiae Fructus extracts with bio-conversion process has effect of skin whitening and anti-inflammation activity than other extracts. It could be used as a valuable materials for functional cosmetics.
 Keywords
Forsythiae Fructus;Lactobacillus;Antioxidant Activity;Bio-Conversion;
 Language
Korean
 Cited by
1.
와송 추출물의 항산화 활성 및 항노화 효과,정다정;최태부;

한국유화학회지, 2016. vol.33. 2, pp.361-373 crossref(new window)
2.
복합 고온 전처리 더덕 추출물의 미백 활성 탐색,김지선;김지웅;권희석;임혜원;이현용;

한국약용작물학회지, 2013. vol.21. 1, pp.54-60 crossref(new window)
3.
가미온청음(加味溫淸飮) 추출물이 항염증, 항산화 및 미백에 미치는 효과,최유진;노정두;

Journal of Acupuncture Research, 2015. vol.32. 3, pp.117-126 crossref(new window)
1.
Screening of Skin Whitening Activity of Codonopsis lanceolata Extract by Complex Steaming Process, Korean Journal of Medicinal Crop Science, 2013, 21, 1, 54  crossref(new windwow)
2.
Effects of -decoction Water-extract on Anti-inflammation, Anti-oxidation and Skin Whitening, The Acupuncture, 2015, 32, 3, 117  crossref(new windwow)
 References
1.
Bae JH, Kim YH and Jang JY. (2005). Antimicrobial effect of forsythiae fructus extracts on several food-borne pathogens. Korean Journal of Food and Cookery Science. 3:319-325.

2.
Boje KM and Arora PK. (1992). Microglial-produced nitric oxide and reactive nitrogen oxides mediate neuronal cell death. Brain Research. 587:250-256 crossref(new window)

3.
Cho SY, Han YB and Shin KH. (2001). Screening for antioxidant activity of edible plants. Journal of the Korean Society of Food Science and Nutrition. 30:133-137.

4.
Choi IS. (2009). Verification of effect with skin phamacological material and cosmetic application from medicinal plant. M.A thesis. Daegu Haany University. Daegu, Korea.

5.
Geun PC, Choi WY, Seo YC, Kang HY, Choi GP and Lee HY. (2010). Anticancer activity of acer mono wood extracted by ultra high pressure extraction process. Korean Journal of Medicinal Crop Science. 18:157-167.

6.
Gutfinger T. (1981). Polyphenols in olive oils. Journal of the American Oil Chemist`s Society. 58:966-968. crossref(new window)

7.
Hatano T, Edamatsu R, Hiramatsu M, Mori A, Fujita Y, Yasuhara T, Yoshida T and Okuda T. (1989). Effect of the interaction of tannins with coexisting substances. Chemical and Pharmaceutical Bulletin. 37:2016-2021. crossref(new window)

8.
Jeong HS, Ha JH, Kim Y, Oh SH, Kim SS, Jeong MH and Lee HY. (2009). Effect of Rubus coreanus extracts on ultraviolet-a irradiated cultured human skin fibroblasts. Korean Journal of Medicinal Crop Science. 17:321-327.

9.
Jin L, Ha JH, Choi YY, Seo YC, Kim JS, Kim YO, Cha SW, Kim JC and Lee HY. (2011). Enhancement of cosmeceutical activities of berberis koreana bark by high pressure and ultrasonification extraction processes. Korean Journal of Medicinal Crop Science. 19:54-65. crossref(new window)

10.
Kaizu H, Sasaki M, Nakajima H and Suzuli Y. (1993). Effect of antioxidative lactic acid bacteria in rats fed a diet deficient in vitamin. Journal of Dairy Science. 76:2493-2499. crossref(new window)

11.
Kang HS, Kim SH, Gim SB, Kim SM and Kim DH. (2011). Effect of cheongyeoltang (cyt) using bioconversion on atopic dermatitis. Institute of Traditional Medicine and Bioscience. Daejeon University. Daejeon, Korea. 19:2.

12.
Kim MJ, Kim JY, Jung TK, Choi SW and Yoon KS. (2006). Skin anti-aging effect of Foysythia viridissima L. extract. Korean Journal of Biotechnology Bioengineering. 21:444-450.

13.
Kim DH. (2009a). Enhancement of antioxidant activities and antiaging of spirulina extracts by fermentation processes. M.A thesis. Dong-Guk University. Seoul, Korea.

14.
Kim SH. (2009b). Physiological activity biotransformation of ginsenosides isolated from ginseng leaves. M.A thesis. Kyonggi University. Gyeonggi-do, Korea.

15.
Kim MJ. (2010). Production oxyresveratrol from mulberry root extract by biotransformation. M.A thesis. Korea Polytechnic University. Gyeonggi-do, Korea.

16.
Kwon SH. (2007). Production of natural butter lactones via microbial biotransformation M.A thesis. Sejong University. Seoul, Korea.

17.
Lee JY. (2007). Inhibitory actions of arctigenin from Forsythiae Fructus on the inflammation and hypersensitivity. Ph.D thesis. Chungang University. Seoul, Korea.

18.
Lee JM, Choi SW, Cho SH and Rhee SJ. (2003). Effect of Forsythia viridissima extracts on antioxidatives system and liver in rats fed high-cholesterol diet. The Korean Journal of Nutrition. 36:990-996.

19.
Marklund S and Marklund G. (1974). Involvement of superoxide anion radical in the auto oxidation of pyrogallol and a convenient assay for superoxide dismutase. European Journal of Biochemistry. 47:469-474. crossref(new window)

20.
Moon YH and Ha CJ. (1977). Effect of Forsythiae Fructus water extract on the blood in the rabbit. The Annual Convention of The Korean Society of Pharmacognosy. 8:177.

21.
Moon YG, Yeo IK and Heo MS. (2007). Growth and antioxidant activity on lactic acid bacteria and antimicrobial activity on fish pathogenic bacteria. Journal of Life Science. 17:1547-1554. crossref(new window)

22.
Moreno M, Isla M, Sampietro A and Vattuone M. (2000). Comparison of the free radical scavenging activity of propolis from several region of Aargentian. Journal of Ethnopharmacology. 71:109-114. crossref(new window)

23.
Nishibe S, Okabe K, Tsukamoto H, Baku-shima A and Hisada S. (1982). The structure and antibacterial activity of suspensaside isolated from Forsythia suspensa. Chemical and Pharmaceutical Bulletin. 30:4548-4553 crossref(new window)

24.
Park HJ. (2010). Study on the cosmeceuticals using enzymetreated red ginseng extracts. Ph.D thesis. Dongduck Womens University. Seoul, Korea.

25.
Shin DH, Kim MS and Han JS. (1997). Antimicrobial effect of ethanol extracts from some medicinal herbs and their fractionates against food-born bacteria. Korean Journal of Food Science Technology. 29:808-816.

26.
Yu BJ. (2007). Effect of Forsythiae Fructus extract on the release of inflammatory mediators induced by lipopolysaccharie in raw 264.7 macrophage. Ph.D thesis. Semyung University. Seoul, Korea.