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Antioxidant and Anticancer Properties of the Extracts from Lepisorus thunbergianus (Kaulf.) Ching
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 Title & Authors
Antioxidant and Anticancer Properties of the Extracts from Lepisorus thunbergianus (Kaulf.) Ching
Yang, Jinfeng; Kwon, Yong Soo; Lim, Jung Dae; Yu, Chang Yeon; Kim, Myong Jo;
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Lepisorus thunbergianus (Kaulf.) Ching has been used in folk medicine in Korea. In this study, a L. thunbergianus methanol extract and its fractions were investigated for their antioxidant properties. The results showed that the ethyl acetate and butanol fractions of L. thunbergianus possess potent DPPH radical scavenging activities. Both fractions also possessed reducing power and inhibited reactive oxygen species formation. In addition, the cytotoxic activity of the L. thunbergianus n-hexane fraction (HF) was investigated. The results suggested that the HF remarkably suppressed proliferation of human breast, liver and colon cancer cells. These results demonstrate, for the first time, that L. thunbergianus extract induces apoptosis in SW620 cells, suggesting that L. thunbergianus may have potential as a therapeutic agent for colon cancer.
Lepisorus thunbergianus (Kaulf.) Ching;Antioxidant;Anticancer;Apoptosis;
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당뇨를 유도한 동물모델에서 지유 추출물의 항산화 활성,조진하;배은영;이태경;김명현;이승웅;김병수;임치환;

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