JOURNAL BROWSE
Search
Advanced SearchSearch Tips
Correlation between Microvascular Density and Matrix Metalloproteinase 11 Expression in Prostate Cancer Tissues: a Preliminary Study in Thailand
facebook(new window)  Pirnt(new window) E-mail(new window) Excel Download
 Title & Authors
Correlation between Microvascular Density and Matrix Metalloproteinase 11 Expression in Prostate Cancer Tissues: a Preliminary Study in Thailand
Kanharat, Nongnuch; Tuamsuk, Panya;
  PDF(new window)
 Abstract
Background: Prostate cancer is a major concern of public health. Microvascular density (MVD) is one of the prognostic markers for various solid cancers. Matrix metalloproteinase 11 (MMP11) plays an important role in angiogenesis and changes in its expression level are known to be associated with tumor progression and clinical outcome. Aim: To investigate the relationship between MVD and MMP11 expression in prostatic adenocarcinoma tissues. Materials and Methods: The expression levels of MMP11 and MVD were analyzed immunohistochemically for 50 specimens of prostatic adenocarcinoma. Results: MMP11 was mainly expressed in stromal cells but rarely seen in epithelial cells. Mean MVD was , and it was correlated significantly only with bone metastases. MVD was also significantly correlated with MMP11 expression (r
 Keywords
Matrix metalloproteinase 11;prostatic adenocarcinoma;Microvascular Density angiogenesis;
 Language
English
 Cited by
1.
Insights into the distinct roles of MMP-11 in tumor biology and future therapeutics (Review), International Journal of Oncology, 2016, 48, 5, 1783  crossref(new windwow)
 References
1.
Basset P, Bellocq JP, Wolf C, et al (1990). A novel Metalloproteinase gene specifically expressed in stromal cells of breast carcinomas. Nature, 348, 699-704. crossref(new window)

2.
Basset P, Wolf C, Chambon P (1993). Expression of the stromelysin-3 gene in fibroblastic cells of invasive carcinomas of the breast and other human tissues: a review. Breast Cancer Res Treat, 24, 185-93. crossref(new window)

3.
Bono AV, Celato N, Cova V, et al (2002). Microvessel density in prostate carcinoma. Prostate Cancer Prostatic Dis, 5, 123-7. crossref(new window)

4.
Choy M, Rafii S (2001). Role of angiogenesis in the progression and treatment of prostate cancer. Cancer Invest, 19, 181-91. crossref(new window)

5.
Concato J, Jain D, Uchio E, et al (2009). Molecular markers and death from prostate cancer. Ann Intern Med, 150, 595-603. crossref(new window)

6.
Condon MS (2005). The role of the stromal microenvironment in prostate cancer. Sem Cancer Biol, 15, 132-7. crossref(new window)

7.
Deryugina EI, Quigley JP (2015). Tumor angiogenesis: MMP-mediated induction of intravasation- and metastasissustaining neovasculature. Matrix Biol, (in press).

8.
Erbersdobler A, Isbarn H, Dix K (2010). Prognostic value of microvessel density in prostate cancer: a tissue microarray study. World J Urol, 28, 687-92. crossref(new window)

9.
Escaff S, Fernandez JM, Gonzalez LO, et al (2010). Study of matrix metalloproteinases and their inhibitors in prostate cancer. Br J Cancer, 102, 922-9. crossref(new window)

10.
Fidler IJ, Ellis LM, (1994). The implications of angiogenesis for the biology and therapy of cancer metastasis. Cell, 79, 185-8. crossref(new window)

11.
Folkman J (1971). Tumor angiogenesis: therapeutic implications. N Engl J Med, 285, 1182-6. crossref(new window)

12.
Folkman J (1990). What is the evidence that tumors are angiogenesis dependent? J Natl Cancer Inst, 82, 4-6. crossref(new window)

13.
Folkman J (1992). The role of angiogenesis in tumor growth. Semin Cancer Biol, 3, 65-71.

14.
Folkman J, Watson K, Ingber D, et al (1989). Induction of angiogenesis during the transition from hyperplasia to neoplasia. Nature, 339, 58-61. crossref(new window)

15.
Gimbrone MA Jr, Leapman SB, Cotran RS, et al (1972). Tumor dormancy in vivo by prevention of neovascularization. J Exp Med, 136, 261-76. crossref(new window)

16.
Globocan (2012). Prostate cancer: estimated incidence, mortality and prevalence worldwide in 2012 [Online]. Available:http://globocan.iarc.fr/Pages/fact_sheets_cancer.aspx.

17.
Iakovlev VV, Gabril M, Dubinski W, et al (2012). Microvascular density as an independent predictor of clinical outcome in renal cell carcinoma: an automated image analysis study. Laboratory Investigation, 92, 46-56. crossref(new window)

18.
Kaygusuz G, Tulunay O, Baltaci S, et al (2007). Microvessel density and regulators of angiogenesis in malignant and nonmalignant prostate tissue. Int Urol Nephrol, 39, 841-50. crossref(new window)

19.
Kessenbrock K, Plaks V, Werb (2010). Matrix Metalloproteinases: Regulators of the Tumor Microenvironment. Cell, 141, 52-67. crossref(new window)

20.
Khuhaprema T, Srivatanakul P, Attasara P, et al (2013). Cancer in Thailand Volume VII 2007-2009. National cancer institute, 7, 12.

21.
Lin CW, Yang SF, Chuang CY, et al (2014). Association of matrix metalloproteinase-11 polymorphisms with susceptibility and clinicopathologic characteristics for oral squamous cell carcinoma. Head Neck, DOI: 10.1002/hed.23771.

22.
Manes S, Mira E, Barbacid MD, et al (1997). Identification of insulin-like growth factor-binding protein-1 as a potential physiological substrate for human stromelysin-3. J Biol Chem, 272, 25706-12. crossref(new window)

23.
Min KW, Kim DH, Do SI, et al (2013). Diagnostic and prognostic relevance of MMP-11 expression in the stromal fibroblastlike cells adjacent to invasive ductal carcinoma of the breast. Ann Surg Oncol, 20, 433-42. crossref(new window)

24.
Montironi R, Diamanti L, Thompson D, et al (1996). Analysis of the capillary architecture in the precursors of prostate cancer: recent findings and new concepts. Eur Urol, 30, 191-200.

25.
Murphy G, Segain JP, O'Shea M, et al (1993). The 28-kDa N-terminal domain of mouse stromelysin-3- has the general properties of a weak metalloproteinase. J Biol Chem, 268, 15435-41.

26.
Nagase H, Woesser JF Jr (1999). Matrix metalloproteinases. J Bio Chem, 274, 21491-4. crossref(new window)

27.
Nicholson B, Theodorescu D (2004). Angiogenesis and prostate cancer tumor growth. J Cellular Biochemistry, 91, 125-50. crossref(new window)

28.
Nonsrijun N, Mitchai J, Brown K, et al (2013). Overexpression of matrix metalloproteinase 11 in Thai prostatic adenocarcinoma associated with poor survival outcome. Asian Pac J Cancer Prev, 14, 3331-5. crossref(new window)

29.
Pei D, Majmudar G, Weiss SJ, (1994). Hydrolytic inactivation of a breast carcinoma cell-derived serpin by human stromelysin-3. J Biol Chem, 269, 25849-55.

30.
Roscilli G, Cappelletti M, Vitis CD, et al (2014). Circulating MMP11 and specific antibody immune response in breast and prostate cancer patients. J Translational Med, 12, 54. crossref(new window)

31.
Rundhaug JE (2005). Matrix metalloproteinases, angiogenesis, and cancer. J Cell Mol Med, 9, 267-85. crossref(new window)

32.
Sinha AA, Quast BJ, Reddy PK, et al (2004). Microvessel density as a molecular marker for identifying high-grade prostatic intraepithelial neoplasia precursors to prostate cancer. Experimental and Molecular Pathology, 77, 153-9. crossref(new window)

33.
Taille Adl, Katz AE, Bagiella E, et al (2000). Microvessel density as a predictor of PSA recurrence after radical prostatectomy a comparison of CD34 and CD31. Am J Clin Pathol, 113, 555-62. crossref(new window)

34.
Tang Y, Nakada MT, Kesavan P, et al (2005). Extracellular matrix metalloproteinase inducer stimulates tumor angiogenesis by elevating vascular endothelial cell growth factor and matrix metalloproteinases. Cancer Res, 65, 3193-9.

35.
Tuamsuk P, Nonsrijun N, Pachirat K, et al (2011). Prostate cancer in Srinagarind Hospital. Srinagarind Med J, 26, 373-6.

36.
van Moorselaar RJ, Voest EE (2002). Angiogenesis in prostate cancer: its role in disease progression and possible therapeutic approaches. Molecular and Cellular Endocrinology, 197, 239-50. crossref(new window)

37.
Weidner N, Carroll PR, Flax J, et al (1993). Tumor angiogenesis correlates with metastasis in invasive prostate carcinoma. Am J Pathol, 143, 401-9,

38.
Yodavudh S, Tangjitgamol S, Puangsa-art S (2008). Prognostic significance of microvessel density and mast cell density for the survival of Thai patients with primary colorectal cancer. J Med Assoc Thai, 91, 723-32.

39.
Zhao ZS, Chu YQ, Ye ZY, et al (2010). Overexpression of matrix metalloproteinase 11 in human gastric carcinoma and its clinicopathologic significance. Hum Pathol, 41, 686-96. crossref(new window)