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Accuracy of Sentinel Node in Detecting Lymph Node Metastasis in Primary Endometrial Carcinoma
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 Title & Authors
Accuracy of Sentinel Node in Detecting Lymph Node Metastasis in Primary Endometrial Carcinoma
Farghali, Mohamed M; Allam, Ihab S; Abdelazim, Ibrahim A; El-Kady, Osama S; Rashed, Ahmed R; Gareer, Waheed Y; Sweed, Mohammed S;
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Background: Endometrial carcinoma is the most common gynecological cancer and its treatment is still controversial, especially in its early stages. There are conflicting data about the efficacy of retroperitoneal lymphadenectomy during abdominal hysterectomy and bilateral salpingoophrectomy treatment. Lymphadenectomy carries a risk of severe complications, especially in women with co-morbidities. Selective lymphadenectomy has been widely employed for staging evaluation of endometrial carcinoma because it is simple and seems to provide reliable data regarding nodal metastasis. This study was designed to evaluate accuracy of sentinel node sampling in detecting lymph node metastasis in primary endometrial carcinoma during staging laparotomy. Materials and Methods: Ninety-three women with endometrial carcinoma at high-risk for nodal metastasis were studied. During laparotomy, methylene blue dye was injected into sub-serosal myometrium, then retroperitoneal spaces were opened and blue lymph nodes within pelvic and para-aortic regions were removed as separate specimens for histopathological examination (sentinel lymph nodes
Sentinel lymph node;endometrial;carcinoma;lymph nodemetastasis;prediction;
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