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Diabetes is an Important Risk Factor for Metastasis in Non-Muscle-Invasive Bladder Cancer
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 Title & Authors
Diabetes is an Important Risk Factor for Metastasis in Non-Muscle-Invasive Bladder Cancer
Ozer, Kutan; Horsanali, Mustafa Ozan; Gorgel, Sacit Nuri; Ozbek, Emin;
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 Abstract
Background: Epidemiological evidence indicates that individuals with diabetes mellitus (DM) may have a modestly increased risk of bladder cancer. In the present study, we aimed to show any association between DM and risk of metastasis in patients with non-muscle-invasive bladder cancer (NMIBC). Materials and Methods: We retrospectively analyzed 698 patients between January 2007 and December 2014 who were diagnosed with and underwent transurethral resection of bladder tumors (TUR-BT). Comparisons of means was conducted by independent samples t test, and relations between categorical variables were investigated by non-parametric chi-square test. A p value of 0.05 was accepted as statistically significant in comparisons. Results: We analyzed 418 patients with non muscle invasive bladder cancer. 123 of whom were diabetic and 295 non-diabetic. In diabetic patients, 13 were N1 stage and 11 M1 stage. When compared with non diabetic patients that was statistically significant (p<0.001). TNM stages were more advanced in diabetic patients (p<0.001), but concurrent CIS (p
 Keywords
Bladder cancer;diabetes mellitus;non-muscle-invasive;metastasis risk;
 Language
English
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