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Predictors of Positive Bone Metastasis in Newly Diagnosed Prostate Cancer Patients
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 Title & Authors
Predictors of Positive Bone Metastasis in Newly Diagnosed Prostate Cancer Patients
Chien, Tsu-Ming; Lu, Yen-Man; Geng, Jiun-Hung; Huang, Tsung-Yi; Ke, Hung-Lung; Huang, Chun-Nung; Li, Ching-Chia; Chou, Yii-Her; Wu, Wen-Jeng; Huang, Shu-Pin;
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Background: The prevalence of prostate cancer (PCa) has been increasing in recent years. Treatment strategies are largely based on the results of bone scan screening. Therefore, our aim was to investigate predictors of positive bone metastasis in newly diagnosed PCa patients. Materials and Methods: After extensive review, 336 consecutive patients newly diagnosed with PCa between April 2010 and November 2013 at our institution were enlisted in the study. Patients were divided into two groups according to bone scan results. Univariate analyses (Chi-square test for discrete variables and independent t-test for continuous variables) were applied to determine the potentially significant risk factors associated with distant bone metastasis. Binary logistic regression analyses were used to further investigate the influence of these factors on bone metastasis. Results: The patient mean age was (range: 48 to 94 years). The mean prostate specific antigen (PSA) level and biopsy Gleason score were and , respectively. The body mass index (BMI) for the series was . Sixty-four patients (19.0%) had a positive bone scan result. Patients with positive bone scan results had a significantly lower BMI ( vs. ; p
Prostate cancer;bone metastasis;prostate specific antigen;predictive actors;
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